Evidence map›Paper›PMID 37968393›Full record

ArticleNature2023

Bacterial cGAS senses a viral RNA to initiate immunity.

Dalton V Banh, Cameron G Roberts, Adrian Morales-Amador, Brandon A Berryhill, Waqas Chaudhry, Bruce R Levin, Sean F Brady, Luciano A Marraffini

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 54 citations in OpenAlex.

  1. How bacterial immune systems sense phage infection.Nature reviews. Microbiology · 2026
    Review
  2. Revisiting the life cycle of temperate phages.Nature reviews. Microbiology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Expanding roles of cGAS-STING signaling in neuroinflammation.The Journal of clinical investigation · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. CBASS limits bacteriophage production while maintaining cell viability inbioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Dalton V Banh *Laboratory of Bacteriology, The Rockefeller University, New York, NY, USA.ORCID 0000-0001-8167-9358
Cameron G Roberts *Laboratory of Bacteriology, The Rockefeller University, New York, NY, USA.
Adrian Morales-AmadorLaboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.ORCID 0000-0001-7944-308X
Brandon A BerryhillDepartment of Biology, Emory University, Atlanta, GA, USA.
Waqas ChaudhryDepartment of Biology, Emory University, Atlanta, GA, USA.
Bruce R LevinDepartment of Biology, Emory University, Atlanta, GA, USA.ORCID 0000-0003-3600-2780
Sean F BradyLaboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.ORCID 0000-0001-5967-8586
Luciano A MarraffiniLaboratory of Bacteriology, The Rockefeller University, New York, NY, USA. marraffini@rockefeller.edu.ORCID 0000-0002-9163-0969
Emory University · USRockefeller University · USCornell University · USHoward Hughes Medical Institute · US

Funding

Weill Cornell/Rockefeller/Sloan-Kettering MST ProgramT32GM007739 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HSU, KATHARINE C · 1985 to 2023
$51.1M
Immunity and Infectious DiseaseT32AI070084 · NIAID · ROCKEFELLER UNIVERSITY · PI Michel C Nussenzweig · 2008 to 2026
$3.3M
Elucidating how CRISPR-Cas Modulates the Spread of S. aureus Pathogenicity IslandsF30AI157535 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI BANH, DALTON VAN · 2021 to 2024
$203k
NIAID NIH HHS F30 AI157535NIAID NIH HHS T32 AI070084NIGMS NIH HHS T32 GM007739
6 · The paper itself

Abstract

Cyclic oligonucleotide-based antiphage signalling systems (CBASS) protect prokaryotes from viral (phage) attack through the production of cyclic oligonucleotides, which activate effector proteins that trigger the death of the infected host

Indexed as

BacteriaNucleotidyltransferasesRNA, ViralStaphylococcus Phages2',5'-Oligoadenylate SynthetaseAnimalsEvolution, MolecularImmunity, InnateOligonucleotidesSignal Transduction2',5'-Oligoadenylate SynthetaseNucleotidyltransferasesOligonucleotidesRNA, Viral

Identifiers

PMID37968393
PMCPMC10686824
OpenAlexW4388694358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.