Evidence map›Paper›PMID 37968126›Full record

ArticleOccupational and environmental medicine2024

Chronic respiratory symptoms following deployment-related occupational and environmental exposures among US veterans.

Eric Garshick, Carrie A Redlich, Anna Korpak, Andrew K Timmons, Nicholas L Smith, Karen Nakayama, Coleen P Baird, Paul Ciminera, Farrah Kheradmand, Vincent S Fan and 11 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Occupational and environmental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02825654 (CSP #595 - Pulmonary Health and Deployment to Southwest Asia and Afghanistan), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02825654 enrolling by invitationnot on this map

CSP #595 - Pulmonary Health and Deployment to Southwest Asia and Afghanistan

Typeobservational_patient_registrySponsorVA Office of Research and DevelopmentRan2018 to 2029Enrolled6,200ConditionsPulmonary Function
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 15 institutions in 1 country.

Eric GarshickPulmonary, Allergy, Sleep, and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, West Roxbury, Massachusetts, USA eric.garshick@va.gov.ORCID 0000-0001-5931-5638
Carrie A RedlichOccupational and Environmental Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-6486-6725
Anna KorpakSeattle Epidemiologic Research and Information Center, Department of Veteran Affairs Office of Research and Development, VA Puget Sound Health Care System Seattle Division, Seattle, Washington, USA.
Andrew K TimmonsSeattle Epidemiologic Research and Information Center, Department of Veteran Affairs Office of Research and Development, VA Puget Sound Health Care System Seattle Division, Seattle, Washington, USA.
Nicholas L SmithSeattle Epidemiologic Research and Information Center, Department of Veteran Affairs Office of Research and Development, VA Puget Sound Health Care System Seattle Division, Seattle, Washington, USA.
Karen NakayamaSeattle Epidemiologic Research and Information Center, Department of Veteran Affairs Office of Research and Development, VA Puget Sound Health Care System Seattle Division, Seattle, Washington, USA.
Coleen P BairdMedical Science Affiliates, Columbia, Maryland, USA.
Paul CimineraHealth Services Policy and Oversight, Office of the Assistant Secretary of Defense for Health Affairs, Washington, District of Columbia, USA.
Farrah KheradmandDepartment of Medicine, Michael E DeBakey VA Medical Center, Houston, Texas, USA.
Vincent S FanVA Puget Sound HCS Seattle Division, Seattle, Washington, USA.
Jaime E HartHarvard Medical School, Brigham and Women's Hospital Channing Division of Network Medicine, Boston, Massachusetts, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T H Chan School of Public Health, Boston, Massachusetts, USA.
Ware KuschnerVA Palo Alto Health Care System, Palo Alto, California, USA.
Octavian IoachimescuClement J. Zablocki VA Medical Center, Milwaukee, Wisconsin, USA.
Michael JerrettUniversity of California Los Angeles Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA.
Phillipe R MontgrainVA San Diego Healthcare System, San Diego, California, USA.
Susan P ProctorUS Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Emily S WanPulmonary, Allergy, Sleep, and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, West Roxbury, Massachusetts, USA.
Christine H WendtPulmonary, Allergy, Critical Care, and Sleep Medicine, Minneapolis VA Medical Center, Minneapolis, Minnesota, USA.
Cherry WongtrakoolAtlanta VA Medical Center, Decatur, Georgia, USA.
Paul D BlancSan Francisco VA Health Care System, San Francisco, California, USA.ORCID 0000-0001-9043-175X
Brigham and Women's Hospital · USVA Puget Sound Health Care System · USUniversity of Washington · USEmory University · USHarvard University · USMedical College of Wisconsin · USMichael E. DeBakey VA Medical Center · USOffice of the Secretary of Defense · USUniversity of California, Los Angeles · USUniversity of California San Diego · USUniversity of California, San Francisco · USUniversity of Minnesota · USU.S. Army Research Institute of Environmental Medicine · USVA Palo Alto Health Care System · USYale University · US

Funding

Targeted Research Training CoreT42OH008429 · OH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARRIS ADAMSON, CARISA · 2005 to 2024
$30.0M
Intramural VA VA999999NIOSH CDC HHS T42 OH008429
6 · The paper itself

Abstract

objectivesCharacterise inhalational exposures during deployment to Afghanistan and Southwest Asia and associations with postdeployment respiratory symptoms.

methodsParticipants (n=1960) in this cross-sectional study of US Veterans (Veterans Affairs Cooperative Study 'Service and Health Among Deployed Veterans') completed an interviewer-administered questionnaire regarding 32 deployment exposures, grouped a priori into six categories: burn pit smoke; other combustion sources; engine exhaust; mechanical and desert dusts; toxicants; and military job-related vapours gas, dusts or fumes (VGDF). Responses were scored ordinally (0, 1, 2) according to exposure frequency. Factor analysis supported item reduction and category consolidation yielding 28 exposure items in 5 categories. Generalised linear models with a logit link tested associations with symptoms (by respiratory health questionnaire) adjusting for other covariates. OR were scaled per 20-point score increment (normalised maximum=100).

resultsThe cohort mean age was 40.7 years with a median deployment duration of 11.7 months. Heavy exposures to multiple inhalational exposures were commonly reported, including burn pit smoke (72.7%) and VGDF (72.0%). The prevalence of dyspnoea, chronic bronchitis and wheeze in the past 12 months was 7.3%, 8.2% and 15.6%, respectively. Burn pit smoke exposure was associated with dyspnoea (OR 1.22; 95% CI 1.06 to 1.47) and chronic bronchitis (OR 1.22; 95% CI 1.13 to 1.44). Exposure to VGDF was associated with dyspnoea (OR 1.29; 95% CI 1.14 to 1.58) and wheeze (OR 1.18; 95% CI 1.02 to 1.35).

conclusionExposures to burn pit smoke and military occupational VGDF during deployment were associated with an increased odds of chronic respiratory symptoms among US Veterans.

Indexed as

Bronchitis, ChronicOccupational ExposureVeteransAdultCross-Sectional StudiesDustDyspneaEnvironmental ExposureGasesHumansSmokeDustGasesSmokeair pollutionoccupational healthrespiratory system

Identifiers

PMID37968126
PMCPMC10872566
OpenAlexW4388705753

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.