Evidence map›Paper›PMID 37967435›Full record

ArticleGastroenterology & hepatology2009

Prevention and Treatment Options for Postoperative Crohn's Disease: A Clinical Dilemma.

Kofi Clarke, Miguel Regueiro

Open access · greenAbstract read
In one paragraph

Article in Gastroenterology & hepatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Kofi ClarkeDr. Clarke is a fellow in the Division of Gastroenterology, Hepatology, and Nutrition at the University of Pittsburgh School of Medicine.
Miguel RegueiroDr. Regueiro serves as Associate Professor of Medicine in the Division of Gastro-enterology, Hepatology, and Nutrition at the University of Pittsburgh School of Medicine, where he is Co-Director of the Inflammatory Bowel Disease Center and Director of the Gastroenterology, Hepatology, and Nutrition Fellowship Program.
Clark University · USNutrition Sciences (Belgium) · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of patients with Crohn's disease require surgery for disease-related complications. Postoperative Crohn's disease recurrence is common after intestinal resection. The optimal management strategy for postoperative recurrence of Crohn's disease is controversial. In the absence of universally adopted guidelines, clinicians and patients must discuss and weigh the risks and benefits of postoperative pharmacotherapy. Those patients at low risk of disease recurrence may not require treatment. On the other hand, patients with more aggressive disease and high risk of recurrence may be best treated early in the postoperative period with an immunomodulator or antitumor necrosis factor agents. Ideally, postoperative treatment decisions would be made using predictable, reliable, and reproducible clinical prediction criteria that would guide treatment. This article reviews the data on postoperative Crohn's disease, including predictors of early recurrence, available options for postoperative monitoring, timing of initiation, and choice of postoperative therapy for prevention and management.

Indexed as

5-aminosalicylatesCrohn’s diseaseimmunomodulatorsinfliximabpostoperative recurrence

Identifiers

PMID37967435
PMCPMC2886401
OpenAlexW121726763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.