Evidence map›Paper›PMID 37967199›Full record

ArticleScience translational medicine2023

Effects of boosting and waning in highly exposed populations on dengue epidemic dynamics.

Rosemary A Aogo, Jose Victor Zambrana, Nery Sanchez, Sergio Ojeda, Guillermina Kuan, Angel Balmaseda, Aubree Gordon, Eva Harris, Leah C Katzelnick

Open access · greenAbstract read
In one paragraph

Article in Science translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Observational
  6. Variations in annual dengue intensities are explained by temperature anomalies.medRxiv : the preprint server for health sciences · 2025
    Article
  7. Climate warming is expanding dengue burden in the Americas and Asia.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Climate warming is expanding dengue burden in the Americas and Asia.medRxiv : the preprint server for health sciences · 2025
    Article
  13. Reconciling heterogeneous dengue virus infection risk estimates from different study designs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Rosemary A AogoViral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-3203, USA.ORCID 0000-0003-4588-4914
Jose Victor ZambranaSustainable Sciences Institute, Managua 14007, Nicaragua.ORCID 0000-0003-0107-6173
Nery SanchezSustainable Sciences Institute, Managua 14007, Nicaragua.ORCID 0000-0002-0070-3895
Sergio OjedaSustainable Sciences Institute, Managua 14007, Nicaragua.ORCID 0000-0003-2512-2306
Guillermina KuanSustainable Sciences Institute, Managua 14007, Nicaragua.ORCID 0000-0002-5251-173X
Angel BalmasedaSustainable Sciences Institute, Managua 14007, Nicaragua.
Aubree GordonDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109-2029, USA.ORCID 0000-0002-9352-7877
Eva HarrisDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA 94720-3370, USA.ORCID 0000-0002-7238-4037
Leah C KatzelnickViral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-3203, USA.ORCID 0000-0003-1033-6758
National Institutes of Health · USSustainable Sciences Institute · USUniversity of Michigan · USMinisterio de Salud · NINational Autonomous University of Nicaragua · NIUniversity of California, Berkeley · US

Funding

Project 3 - Ex vivo immune profiling of dengue viruses and vaccinesU19AI118610 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MERAD, MIRIAM · 2015 to 2021
$46.6M
T Cell Responses Following DENV Natural Infections and Live-Attenuated Dengue Virus VaccinationP01AI106695 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Daniela Weiskopf · 2015 to 2026
$34.1M
Living in the post-Zika world: Impact of interactions between dengue and Zika viruses on diagnostics, antibody dynamics, and correlates of disease riskU01AI153416 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARRIS, EVA · 2021 to 2025
$4.9M
Flu Dynamics COVID-19 SupplementR01AI120997 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GORDON, AUBREE L · 2017 to 2021
$4.1M
Epidemiological, Clinical & Immunological Studies of Zika, dengue and chikungunyaR01AI099631 · NIAID · SUSTAINABLE SCIENCES INSTITUTE · PI BALMASEDA, ANGEL LAZARO · 2012 to 2021
$1.8M
NIAID NIH HHS HHSN272201000026CNIAID NIH HHS HHSN272201400006CNIAID NIH HHS P01 AI106695NIAID NIH HHS R01 AI099631NIAID NIH HHS R01 AI120997NIAID NIH HHS U01 AI153416NIAID NIH HHS U19 AI118610
6 · The paper itself

Abstract

Sequential infection with multiple dengue virus (DENV) serotypes is thought to induce enduring protection against dengue disease. However, long-term antibody waning has been observed after repeated DENV infection. Here, we provide evidence that highly immune Nicaraguan children and adults (

Indexed as

DengueDengue VirusZika VirusZika Virus InfectionAdultAntibodies, ViralChildCross ReactionsHumansAntibodies, Viral

Identifiers

PMID37967199
PMCPMC11001200
OpenAlexW4388692463

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.