Evidence map›Paper›PMID 37967185›Full record

ArticleScience advances2023

Centromere innovations within a mouse species.

Craig W Gambogi, Nootan Pandey, Jennine M Dawicki-McKenna, Uma P Arora, Mikhail A Liskovykh, Jun Ma, Piero Lamelza, Vladimir Larionov, Michael A Lampson, Glennis A Logsdon and 2 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Molecular evolution of the mammalian kinetochore complex.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Craig W GambogiDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.ORCID 0000-0001-7118-8942
Nootan PandeyDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
Jennine M Dawicki-McKennaDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.ORCID 0000-0002-1293-640X
Uma P AroraThe Jackson Laboratory, Bar Harbor, ME 04609, USA.
Mikhail A LiskovykhDevelopmental Therapeutics Branch, National Cancer Institute, Bethesda, MD 20892, USA.ORCID 0000-0002-6760-8331
Jun MaDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-6430-1959
Piero LamelzaDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-4943-5756
Vladimir LarionovDevelopmental Therapeutics Branch, National Cancer Institute, Bethesda, MD 20892, USA.
Michael A LampsonDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-2825-1894
Glennis A LogsdonDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.ORCID 0000-0003-2396-0656
Beth L DumontThe Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0003-0918-0389
Ben E BlackDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.ORCID 0000-0002-3707-9483
Penn Center for AIDS Research · USUniversity of Pennsylvania · USNational Cancer Institute · USTufts University · USUniversity of Washington · US

Funding

Cell Biological mechanisms of centromere driveR35GM122475 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Michael Lampson · 2017 to 2026
$4.5M
Centromere identity, strength, and regulationR35GM130302 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Ben E. Black · 2019 to 2026
$4.3M
Population genomics in laboratory and outbred mouse populationsR35GM133415 · NIGMS · JACKSON LABORATORY · PI BETHANY L DUMONT · 2019 to 2026
$3.1M
Investigating the regulation of Aurora B levels at the centromereF32GM108360 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DAWICKI MCKENNA, JENNINE M · 2014 to 2015
$109k
Human centromere variation and functionK99GM147352 · NIGMS · UNIVERSITY OF WASHINGTON · PI LOGSDON, GLENNIS AMELIA · 2022 to 2022
$100k
Defining the effect of centromere/kinetochore associations on genome instabilityF31CA268727 · NCI · TUFTS UNIVERSITY BOSTON · PI ARORA, UMA · 2022 to 2022
$42k
NCI NIH HHS F31 CA268727NIGMS NIH HHS F32 GM108360NIGMS NIH HHS K99 GM147352NIGMS NIH HHS R35 GM122475NIGMS NIH HHS R35 GM130302NIGMS NIH HHS R35 GM133415
6 · The paper itself

Abstract

Mammalian centromeres direct faithful genetic inheritance and are typically characterized by regions of highly repetitive and rapidly evolving DNA. We focused on a mouse species,

Indexed as

AutoantigensChromosomal Proteins, Non-HistoneAnimalsCentromereCentromere Protein AMammalsMiceNucleosomesAutoantigensCentromere Protein AChromosomal Proteins, Non-HistoneNucleosomes

Identifiers

PMID37967185
PMCPMC10651114
OpenAlexW4388711612

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.