Evidence map›Paper›PMID 37966788›Full record

ArticleOptics letters2023

Decoding diffuse light scattering dynamics in layered tissues: path length versus fluctuation time scale.

Santosh Aparanji, Mingjun Zhao, Vivek J Srinivasan

Open access · greenAbstract read
In one paragraph

Article in Optics letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Comprehensive Optimization of Interferometric Diffusing Wave Spectroscopy (iDWS).IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Santosh Aparanji
Mingjun Zhao
Vivek J Srinivasan
NYU Langone Health · US

Funding

TRD3: Data Analytics and Intelligent Systems (AI-ML-DL-Visualization)P41EB032840 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Griffith R. Harsh · 2022 to 2026
$6.7M
True Sub-Micron Ocular Diagnostics with Visible Light Optical Coherence TomographyR01EY031469 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SRINIVASAN, VIVEK JAY · 2020 to 2023
$2.3M
Human Brain Interferometers for Better Blood Flow MonitoringR01EB029747 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SRINIVASAN, VIVEK JAY · 2020 to 2023
$2.2M
NEI NIH HHS R01 EY031469NIBIB NIH HHS P41 EB032840NIBIB NIH HHS R01 EB029747
6 · The paper itself

Abstract

Dynamic multiple light scattering (DMLS) has found numerous applications, including soft matter physics and biomedical optics. Yet biological tissues may have complex internal geometries, presenting a challenge for noninvasive measurements. Deciphering laminar dynamics is crucial to accurately interpret tissue or organ physiology. Seminal DMLS work noted that one can probe deeper layers indirectly by analyzing light fluctuations on shorter time scales. Recent technologies have enabled probing deeper layers directly by analyzing fluctuations at longer path lengths. The following question arises: are the indirect and direct approaches synergistic or redundant? Here, by adding an optical switch to path-length-filtered interferometric diffusing wave spectroscopy, we experimentally address this question in the context of a forearm occlusion study. We find that both approaches afford better distinction of light scattering dynamics in layered tissues than either approach alone. This motivates further development of methods that integrate both decorrelation time scale and light path length to probe layered tissues.

Indexed as

InterferometryOptics and PhotonicsDiffusionSpectrum Analysis

Identifiers

PMID37966788
PMCPMC10935582
OpenAlexW4388141130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.