Evidence map›Paper›PMID 37965540›Full record

ArticleFrontiers in microbiology2023

Alkyl gallates inhibit serine

Touya Toyomoto, Katsuhiko Ono, Tomoo Shiba, Kenta Momitani, Tianli Zhang, Hiroyasu Tsutsuki, Takeshi Ishikawa, Kanae Hoso, Koma Hamada, Azizur Rahman and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Serine Acetyltransferase fromInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. iScience · 2026
    Article
  5. Inhibitors of Serine Acetyltransferase Induce Lethality inACS medicinal chemistry letters · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Touya Toyomoto *Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Katsuhiko Ono *Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Tomoo ShibaDepartment of Applied Biology, Graduate School of Science and Technology, Kyoto Institute of Technology, Kyoto, Japan.
Kenta MomitaniDepartment of Applied Biology, Graduate School of Science and Technology, Kyoto Institute of Technology, Kyoto, Japan.
Tianli ZhangDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Hiroyasu TsutsukiDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Takeshi IshikawaDepartment of Chemistry, Biotechnology, and Chemical Engineering, Graduate School of Science and Engineering, Kagoshima University, Kagoshima, Japan.
Kanae HosoDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Koma HamadaFaculty of Advanced Science and Technology, Kumamoto University, Kumamoto, Japan.
Azizur RahmanDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Liping WenDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Yosuke MaedaDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Keiichi YamamotoDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Masao MatsuokaDepartment of Hematology, Rheumatology, and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Kenjiro HanaokaGraduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
Takuro NiidomeFaculty of Advanced Science and Technology, Kumamoto University, Kumamoto, Japan.
Takaaki AkaikeDepartment of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tomohiro SawaDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Kumamoto University · JPKyoto Institute of Technology · JPKagoshima University · JPKeio University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A principal concept in developing antibacterial agents with selective toxicity is blocking metabolic pathways that are critical for bacterial growth but that mammalian cells lack. Serine

Indexed as

alkyl gallatesantimicrobial resistanceCysE inhibitorscysteinepersulfidesserine O-acetyltransferase

Identifiers

PMID37965540
PMCPMC10641863
OpenAlexW4387998463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.