Evidence map›Paper›PMID 37965353›Full record

ArticleJournal of inflammation research2023

Transcriptomics Analysis Revealed Key Genes Associated with Macrophage Autophagolysosome in Male ApoE

Meirong Zhu, Tongyu Jin, Ding Wu, Shanchao Zhang, Aihua Wang

Abstract read
In one paragraph

Article in Journal of inflammation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meirong ZhuDepartment of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, People's Republic of China.ORCID 0009-0004-7578-9736
Tongyu JinDepartment of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, People's Republic of China.
Ding WuVascular Surgery, Jinan Central Hospital, Jinan, People's Republic of China.
Shanchao Zhang *Department of Neurology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong First Medical University, Jinan, People's Republic of China.ORCID 0000-0002-5543-4530
Aihua Wang *Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Atherosclerosis (AS) is the most common cause of cardiovascular and cerebrovascular diseases. However, the mechanisms underlying atherosclerotic plaque progression remain unclear. This study aimed to investigate the genes associated with the development of atherosclerosis in the aorta of ApoE Methods: Eight-week-old ApoE Results: There were 265 differentially expressed genes (DEGs) between the ApoE Conclusion: Five core genes which affect the development of aortic atherosclerosis through the autophagy-lysosome system, especially

Indexed as

aortic plaque developmentbioinformaticscore genelysosomemolecular mechanism

Identifiers

PMID37965353
PMCPMC10642550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.