Evidence map›Paper›PMID 37965306›Full record

ArticleFrontiers in immunology2023

Structural informatics approach for designing an epitope-based vaccine against the brain-eating

Asifa Sarfraz, Tehreem Ul Wara, Sheheryar, Ke Chen, Shahid Habib Ansari, Aqal Zaman, Umar Nishan, Anwar Iqbal, Riaz Ullah, Essam A Ali and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. International journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Design of a Multi-Epitope Vaccine Based onInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Computer-aided identification ofFrontiers in pharmacology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Asifa Sarfraz *Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
Tehreem Ul Wara *Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
SheheryarDepartment of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil.
Ke ChenDepartment of Infectious Diseases, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Shahid Habib AnsariDepartment of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
Aqal ZamanDepartment of Microbiology & Molecular Genetics, Bahauddin Zakariya University, Multan, Pakistan.
Umar NishanDepartment of Chemistry, Kohat University of Science & Technology, Kohat, Pakistan.
Anwar IqbalDepartment of Chemical Sciences, University of Lakki Marwat, Khyber Pakhtunkhwa, Pakistan.
Riaz UllahDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Essam A AliDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Mohibullah ShahDepartment of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
Suvash Chandra OjhaDepartment of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil.
Bahauddin Zakariya University · PKKing Saud University · SAUniversidade Federal do Ceará · BRAffiliated Hospital of Southwest Medical University · CNGovernment of Khyber Pakhtunkhwa · PKKohat University of Science and Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary Amoebic Meningoencephalitis (PAM), a severe lethal brain disease, is caused by a parasite,

Indexed as

Central Nervous System Protozoal InfectionsNaegleria fowleriBrainEpitopes, B-LymphocyteEscherichia coliHumansInformaticsVaccines, SubunitEpitopes, B-LymphocyteVaccines, Subunitbrain-eatingepitopeimmunoinformaticsNaegleriaparasiteprimary amoebic meningoencephalitisreverse vaccinology

Identifiers

PMID37965306
PMCPMC10642955
OpenAlexW4388106483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.