Evidence map›Paper›PMID 37965096›Full record

ArticleThe World Allergy Organization journal2023

IgE response to Aed al 13 and Aed al 14 recombinant allergens from

Irene Arnoldi, Marta Villa, Giulia Mancini, Ilaria Varotto-Boccazzi, Mona-Rita Yacoub, Chiara Asperti, Ambra Mascheri, Simone Casiraghi, Sara Epis, Claudio Bandi and 3 more

Open access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. RepeatedFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Irene ArnoldiEntopar Lab, Department of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Marta VillaEntopar Lab, Department of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Giulia ManciniThe Armenise-Harvard Laboratory of Structural Biology, Department Biology and Biotechnology, University of Pavia, Via Ferrata 9/A, 27100, Pavia, Italy.
Ilaria Varotto-BoccazziEntopar Lab, Department of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Mona-Rita YacoubUnit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Chiara AspertiUnit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ambra MascheriUnit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Simone CasiraghiUnit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Sara EpisEntopar Lab, Department of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Claudio BandiEntopar Lab, Department of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Lorenzo DagnaUnit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Federico FornerisThe Armenise-Harvard Laboratory of Structural Biology, Department Biology and Biotechnology, University of Pavia, Via Ferrata 9/A, 27100, Pavia, Italy.
Paolo GabrieliEntopar Lab, Department of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
University of Milan · ITVita-Salute San Raffaele University · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mosquito bite is normally associated with mild allergic responses, but severe localized or systemic reactions are also possible. Reliable tools for the diagnosis of mosquito allergy are still unavailable. Here, we investigated the IgE response to 3 potential salivary allergens identified in the saliva of the tiger mosquito Methods: Serum from 55 adult individuals (28 controls and 27 allergic people), were analysed using an in-house Enzyme Linked ImmunoSorbent Assay (ELISA) against the Salivary Gland Extract (SGE) and the recombinant proteins Results: Fifteen of the 27 (56%) individuals having hypersensitive reactions to mosquito bites had IgE serum levels recognizing SGE. Negative sera did not show detectable levels of IgE targeting the SGE from the most common sympatric mosquito Conclusions: Our results indicate that Aed al 13 and Aed al 14 hold the potential to be developed as tools for the diagnosis of allergy to

Indexed as

AllergensCulicidaeInsect proteinsSalivaVenom hypesentivity

Identifiers

PMID37965096
PMCPMC10641722
OpenAlexW4388229401

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.