Evidence map›Paper›PMID 37964974›Full record

ArticleFrontiers in endocrinology2023

Stanniocalcin 1a regulates organismal calcium balance and survival by suppressing Trpv6 expression and inhibiting IGF signaling in zebrafish.

Shuang Li, Helena Li, Zhengyi Wang, Cunming Duan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shuang Li *Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, United States.
Helena Li *Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, United States.
Zhengyi WangDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, United States.
Cunming DuanDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stanniocalcin 1 (Stc1) is well known for its role in regulating calcium uptake in fish by acting on ionocytes or NaR cells. A hallmark of NaR cells is the expression of Trpv6, a constitutively open calcium channel. Recent studies in zebrafish suggest that genetical deletion of Stc1a and Trpv6 individually both increases IGF signaling and NaR cell proliferation. While

Indexed as

CalciumZebrafishAnimalsCalcium, DietaryGlycoproteinsSignal TransductionTRPV Cation ChannelsZebrafish ProteinsCalciumCalcium, DietaryGlycoproteinsteleocalcintrpv6 protein, zebrafishTRPV Cation ChannelsZebrafish Proteinscalcium uptakeIGF signalingionocyteStc1aTrvp6

Identifiers

PMID37964974
PMCPMC10640984
OpenAlexW4388196229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.