Evidence map›Paper›PMID 37964367›Full record

ArticleTrials2023

Multi-center, pragmatic, cluster-randomized, controlled trial of standardized peritoneal dialysis (PD) training versus usual care on PD-related infections (the TEACH-PD trial): trial protocol.

Josephine S F Chow, Neil Boudville, Yeoungjee Cho, Suetonia Palmer, Elaine M Pascoe, Carmel M Hawley, Donna M Reidlinger, Laura E Hickey, Ruth Stastny, Andrea Valks and 28 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03816111 (A Pragmatic, Registry-based, International, Cluster-randomized Controlled Trial Examining the Use of TEACH-PD Training Modules for Incident PD Patients Versus Existing Practices on the Rate of PD-related Infections), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03816111 nacompletednot on this map

A Pragmatic, Registry-based, International, Cluster-randomized Controlled Trial Examining the Use of TEACH-PD Training Modules for Incident PD Patients Versus Existing Practices on the Rate of PD-related Infections

TypeinterventionalSponsorThe University of QueenslandRan2019 to 2025Enrolled1,462ConditionsKidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis, Peritoneal Dialysis Catheter Exit Site Infection, Peritoneal Dialysis Catheter Tunnel InfectionArmsTEACH-PD Training Curriculum, Current standard PD training
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Reducing Bias in Cluster Randomized Trials in Nephrology.Journal of the American Society of Nephrology : JASN · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 18 institutions in 3 countries.

Josephine S F ChowSouth Western Sydney Local Health District, Liverpool, NSW, Australia. Josephine.Chow@health.nsw.gov.au.ORCID http://orcid.org/0000-0002-8911-6856
Neil BoudvilleMedical School, University of Western Australia, Crawley, WA, Australia.
Yeoungjee ChoDepartment of Kidney and Transplant Service, Princess Alexandra Hospital, Brisbane, QLD, Australia.
Suetonia PalmerDepartment of Medicine, University of Otago, Christchurch, New Zealand.
Elaine M PascoeAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Carmel M HawleyAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Donna M ReidlingerCentre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Laura E HickeyAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Ruth StastnyAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Andrea ValksAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Liza VergaraAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Ramya MovvaAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Charani KiriwandeniyaAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Hayley CandlerAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Gabor MihalaAustralasian Kidney Trials Network, Centre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.
Bernadette BuismanHealth New Zealand, Te Whatu Ora Te Tai Tokerau, Hamilton, New Zealand.
Keri-Lu EquinoxCairns Hospital, Cairns, QLD, Australia.
Ana E FigueiredoSchool of Nursing, Escola de Ciências da Saúde E da Vida, Pontifícia Universidade Católica Do Rio Grande Do Sul, Porto Alegre, Brazil.
Trudi Fuge, Wollongong, Australia.
Kirsten HowardSydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.
Martin HowellMenzies Centre for Health Policy and Economics, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
Allison JaureSydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.
Matthew D JoseUniversity of Tasmania, Hobart, TAS, Australia.
Anna Lee, Shoalhaven, Australia.
Susana S MiguelSouth Western Sydney Local Health District, Liverpool, NSW, Australia.
Jo-Anne MoodieRoyal Melbourne Hospital, Parkville, VIC, Australia.
Thu T NguyenHealth New Zealand, Te Whatu Ora Te Toka Tumai, Hamilton, New Zealand.
Geraldine PinlacDepartment of Medicine, University of Otago, Christchurch, New Zealand.
Annie ReynoldsHealth New Zealand, Te Whatu Ora Te Matua a Māui Hawkes Bay, Hamilton, New Zealand.
Walaa W M SaweirsHealth New Zealand, Te Whatu Ora Te Tai Tokerau, Hamilton, New Zealand.
Genevieve Z Steiner-LimNICM Health Research Institute, Western Sydney University Sydney, Campbelltown, NSW, Australia.
Bronwen TeWhareHealth New Zealand, Te Whatu Ora Taranaki, Hamilton, New Zealand.
Melinda TomlinsDepartment of Nephrology, Hunter New England Local Health District, New Lambton, NSW, Australia.
Megan UpjohnHealth New Zealand, Te Whatu Ora Te Toka Tumai, Hamilton, New Zealand.
David VossHealth New Zealand, Te Whatu Ora Counties Manukau, Hamilton, New Zealand.
Rachael C WalkerTe Pukenga Eastern Institute of Technology, Christchurch, New Zealand.
Joanne WilsonDepartment of Medicine, University of Otago, Christchurch, New Zealand.
David W JohnsonDepartment of Kidney and Transplant Service, Princess Alexandra Hospital, Brisbane, QLD, Australia.
The University of Queensland · AUThe University of Sydney · AUUniversity of Otago · NZUniversity of Tasmania · AUCairns Hospital · AUCamden and Campbelltown Hospitals · AUCounties Manukau District Health Board · NZEastern Institute of Technology · NZHunter New England Local Health District · AUIngham Institute · AUPontifícia Universidade Católica do Rio Grande do Sul · BRShoalhaven District Memorial Hospital · AUTaranaki Base Hospital · NZThe Royal Melbourne Hospital · AUThe University of Western Australia · AUTranslational Research Institute · AUUniversity of Auckland · NZWaikato District Health Board · NZ

Funding

Health Research Council of New Zealand 19/290National Health and Medical Research Council APP1092957National Health and Medical Research Council APP1170238
6 · The paper itself

Abstract

backgroundPeritoneal dialysis (PD)-related infections, such as peritonitis, exit site, and tunnel infections, substantially impair the sustainability of PD. Accordingly, PD-related infection is the top-priority research outcome for patients and caregivers. While PD nurse trainers teach patients to perform their own PD, PD training curricula are not standardized or informed by an evidentiary base and may offer a potential approach to prevent PD infections. The Targeted Education ApproaCH to improve Peritoneal Dialysis outcomes (TEACH-PD) trial evaluates whether a standardized training curriculum for PD nurse trainers and incident PD patients based on the International Society for Peritoneal Dialysis (ISPD) guidelines reduces PD-related infections compared to usual training practices.

methodsThe TEACH-PD trial is a registry-based, pragmatic, open-label, multi-center, binational, cluster-randomized controlled trial. TEACH-PD will recruit adults aged 18 years or older who have not previously undergone PD training at 42 PD treatment units (clusters) in Australia and New Zealand (ANZ) between July 2019 and June 2023. Clusters will be randomized 1:1 to standardized TEACH-PD training curriculum or usual training practice. The primary trial outcome is the time to the first occurrence of any PD-related infection (exit site infection, tunnel infection, or peritonitis). The secondary trial outcomes are the individual components of the primary outcome, infection-associated catheter removal, transfer to hemodialysis (greater than 30 days and 180 days), quality of life, hospitalization, all-cause death, a composite of transfer to hemodialysis or all-cause death, and cost-effectiveness. Participants are followed for a minimum of 12 months with a targeted average follow-up period of 2 years. Participant and outcome data are collected from the ANZ Dialysis and Transplant Registry (ANZDATA) and the New Zealand Peritoneal Dialysis (NZPD) Registry. This protocol follows the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) guidelines. DISCUSSION: TEACH-PD is a registry-based, cluster-randomized pragmatic trial that aims to provide high-certainty evidence about whether an ISPD guideline-informed standardized PD training curriculum for PD nurse trainers and adult patients prevents PD-related infections.

trial registrationClinicalTrials.gov NCT03816111. Registered on 24 January 2019.

Indexed as

Peritoneal DialysisPeritonitisAdultCurriculumHumansMulticenter Studies as TopicPragmatic Clinical Trials as TopicQuality of LifeRandomized Controlled Trials as TopicCluster randomized controlled trialCompetency assessmentCost-effectivenessOutcomesPatient educationPeritoneal dialysisPeritonitisStandardized training

Identifiers

PMID37964367
PMCPMC10647147
OpenAlexW4388661993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.