Evidence map›Paper›PMID 37964357›Full record

ReviewJournal of medical case reports2023

Cauda equina syndrome in a patient with human immunodeficiency virus and secondary central nervous system lymphoma: a case report.

Alexander Tang, David Di Fonzo, Mohammed Redha, Michael Churchill-Smith

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Journal of medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander TangDivision of General Internal Medicine, McGill University Health Centre, Montreal, Canada. alexander.tang@mail.mcgill.ca.
David Di FonzoDivision of General Internal Medicine, McGill University Health Centre, Montreal, Canada.ORCID http://orcid.org/0009-0004-9226-8828
Mohammed RedhaDivision of General Internal Medicine, McGill University Health Centre, Montreal, Canada.
Michael Churchill-SmithDivision of General Internal Medicine, McGill University Health Centre, Montreal, Canada.
McGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSecondary central nervous system lymphoma (SCNSL) is a known complication of immunocompromised patients with most cases involving the brain parenchyma. Reports of cauda equina syndrome (CES) caused by SCNSL are exceedingly scarce as involvement of this anatomical region is extremely uncommon. CASE PRESENTATION: We report a case of a 46-years-old, African, female patient with human immunodeficiency virus (HIV) who developed CES in the context of SCNSL. There were no blasts present in the peripheral blood smear. We provide a review of the literature, discussion of the clinical evolution of this patient and the radiological/histopathological findings. The patient ultimately responded well to induction chemotherapy and high dose methotrexate.

conclusionThis case report demonstrates that CES, while a rare occurrence in this clinical context, should be considered in at-risk patients especially those presenting with abnormal neurological findings. Prompt recognition may prevent permanent neurological injury and obviate the need for more invasive therapeutic interventions.

Indexed as

Cauda Equina SyndromeLymphomaCentral Nervous SystemFemaleHIVHumansMiddle AgedCauda equina syndromeHIVImmunocompromisedLymphoma

Identifiers

PMID37964357
PMCPMC10647035
OpenAlexW4388682538

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.