ArticleNutrition journal2023
Association between dietary vitamin C and abdominal aortic calcification among the US adults.
Article in Nutrition journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 19 citations in OpenAlex.
- Predictive nomogram for abdominal aortic calcification risk: a multi-algorithm approach integrating demographic and clinical variables.Journal of cardiothoracic surgery · 2026Article
- Article
- Differential Effects of Vitamin C from Fruit and Vegetables Versus Supplements on the Risk of Frailty.Nutrients · 2025Article
- Pattern of dietary and supplemental vitamin C intake according to the level of fruit and vegetable consumption.Nutrition research and practice · 2025Article
- Association of monocyte-to-high-density lipoprotein-cholesterol ratio level with risk of severe abdominal aortic calcification: a large cross-sectional study based on NHANES.Nutrition & metabolism · 2025Article
- Antioxidant Intervention Against Microplastic Hazards.Antioxidants (Basel, Switzerland) · 2025Review
- The effect of dietary micronutrient intake on abdominal aortic calcification: a study protocol for systematic review and meta-analysis.BMJ open · 2025Article
- Vitamin C in Cardiovascular Disease: From Molecular Mechanisms to Clinical Evidence and Therapeutic Applications.Antioxidants (Basel, Switzerland) · 2025Review
- PMEnvironmental health : a global access science source · 2025Article
- Associations between oxidation balance score and abdominal aortic calcification, and the mediating role of glycohemoglobin: a nationally representative cross-sectional study from NHANES.Frontiers in nutrition · 2025Article
- Oxidative stress in vascular surgical diseases: mechanisms, impacts and therapeutic perspectives.Frontiers in pharmacology · 2025Review
- Composite dietary antioxidant index and abdominal aortic calcification: a national cross-sectional study.Nutrition journal · 2024Article
- Analysis of factors influencing vascular calcification in peritoneal dialysis patients and their impact on long-term prognosis.BMC nephrology · 2024Article
- Relationship Between Dietary Inflammatory Index and Carotid Artery Calcification in Patients with Ischemic Stroke.Journal of inflammation research · 2024Article
- Association between dietary niacin intake and abdominal aortic calcification among the US adults: the NHANES 2013-2014.Frontiers in nutrition · 2024Article
- The relationship between dietary vitamin B1 intake and severe abdominal aortic calcification among the general population in the United States.Frontiers in cardiovascular medicine · 2024Article
- Association of dietary vitamin C consumption with severe headache or migraine among adults: a cross-sectional study of NHANES 1999-2004.Frontiers in nutrition · 2024Article
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundCardiovascular disease (CVD) is the leading cause of mortality, and vascular calcification has been highly correlated with CVD events. Abdominal aortic calcification (AAC) has been shown to predict subclinical CVD and incident CVD events. However, the relationship between vitamin C and abdominal aortic calcification remains unclear.
objectiveTo investigate the relationship of dietary vitamin C with AAC among the adult population in the US.
methodsThe National Health and Nutrition Examination Survey (NHANES) 2013-2014 provided the data for the cross-sectional study. 2297 subjects (1089 males) were included in the study. Two scoring systems, AAC 24-point scale (Kauppila) and AAC 8-point scale (Schousboe), were used for the measurement of AAC score. Dietary vitamin C intake was calculated as the average of two rounds of 24-h interview recall data and classified in tertiles for analysis. We applied weighted multiple regression analyses to assess the relationship of dietary vitamin C with AAC score and the risk of having AAC. To ensure the robustness of the findings, subgroup and sensitivity analyses were performed. Additionally, smooth curve fittings, using generalized additive models (GAM) were employed to visualize potential nonlinear relationships. Furthermore, an exploratory analysis on the relationship of vitamin C supplements with AAC was also conducted.
resultsThe results showed that higher dietary vitamin C intake was related to a reduction in AAC score (AAC-24: β = -0.338, 95% confidence interval [CI] -0.565, -0.111, P = 0.004; AAC-8: β = -0.132, 95%CI -0.217, -0.047, P = 0.002), and lower risk of AAC (odds ratio [OR] = 0.807, 95%CI 0.659, 0.989, P = 0.038). However, the relationship of vitamin C supplements with AAC was not identified.
conclusionsThe study revealed that higher intake of dietary vitamin C rather than vitamin C supplements was related to reduced AAC score and lower risk of AAC, indicating that diets rich in vitamin C are recommended due to its potential benefits for protecting against vascular calcification and CVD among the adult population in the US.
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