Evidence map›Paper›PMID 37964179›Full record

ArticleClinical journal of gastroenterology2024

Acetaminophen-induced liver injury at therapeutic doses in a young adult: a case report.

Satoko Tajirika, Mayumi Yamamoto, Tomomichi Matsushita, Tetsuya Yamada, Masahito Shimizu

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Satoko TajirikaHealth Administration Center, Gifu University, 1-1 Yanagido, Gifu City, Gifu, 501-1193, Japan. tajirika.satoko.z2@f.gifu-u.ac.jp.ORCID http://orcid.org/0000-0003-2447-5783
Mayumi YamamotoHealth Administration Center, Gifu University, 1-1 Yanagido, Gifu City, Gifu, 501-1193, Japan.
Tomomichi MatsushitaDepartment of Gastroenterology, Japanese Red Cross Gifu Hospital, Gifu, 502-8511, Japan.
Tetsuya YamadaDepartment of Pathology, Central Japan International Medical Center, Gifu, 505-8510, Japan.
Masahito ShimizuDepartment of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, Gifu, 501-1194, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetaminophen causes volume-dependent hepatotoxicity; however, hepatotoxicity may also occur with acetaminophen administered at normal doses. We encountered a case of allergic liver damage in a 17-year-old girl receiving acetaminophen at a regular dose. The patient was diagnosed using the Roussel Uclaf Causality Assessment Method (RUCAM) and the diagnostic scale of the Digestive Disease Week Japan 2004 workshop. She tested positive for acetaminophen on a drug-induced lymphocyte stimulation test, and liver biopsy results confirmed the diagnosis of acetaminophen-induced liver injury. Despite administering acetaminophen at normal doses, hepatotoxicity may occur, which warrants further exploration.

Indexed as

Chemical and Drug Induced Liver InjuryChemical and Drug Induced Liver Injury, ChronicLiver DiseasesAcetaminophenAdolescentCausalityFemaleHumansYoung AdultAcetaminophenAcetaminophenDrug-induced liver injuryDrug-induced lymphocyte stimulation testLiver biopsyYoung adult

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.