Evidence map›Paper›PMID 37964137›Full record

ArticleEJNMMI research2023

Characterisation of a novel [

Sameer Omer Jin, Inés Mérida, Ioannis Stavropoulos, Robert D C Elwes, Tanya Lam, Eric Guedj, Nadine Girard, Nicolas Costes, Alexander Hammers

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Sameer Omer JinFaculty of Life Sciences and Medicine, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.ORCID http://orcid.org/0000-0002-1643-2735
Inés MéridaCentre d'Etude et de Recherche Multimodale et Pluridisciplinaire en Imagerie du Vivant (CERMEP), Lyon, France.ORCID http://orcid.org/0000-0003-1436-4684
Ioannis StavropoulosDepartment of Clinical Neurophysiology, King's College Hospital, London, UK.ORCID http://orcid.org/0000-0002-6920-1826
Robert D C ElwesDepartment of Clinical Neurophysiology, King's College Hospital, London, UK.
Tanya LamChildren's Neuroscience Centre, Evelina London Children's Hospital, Guy's and St Thomas' NHS Trust, London, UK.ORCID http://orcid.org/0000-0001-6986-7727
Eric GuedjNuclear Medicine Department, APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Aix Marseille University, Marseille, France.ORCID http://orcid.org/0000-0003-1912-6132
Nadine GirardDepartment of Neuroradiology, APHM, CRMBM, UMR CNRS 7339, Timone Hospital, Aix Marseille University, Marseille, France.ORCID http://orcid.org/0000-0001-8639-9275
Nicolas CostesCentre d'Etude et de Recherche Multimodale et Pluridisciplinaire en Imagerie du Vivant (CERMEP), Lyon, France.ORCID http://orcid.org/0000-0002-2954-9262
Alexander HammersFaculty of Life Sciences and Medicine, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK. alexander.hammers@kcl.ac.uk.ORCID http://orcid.org/0000-0001-9530-4848
King's College London · GBCentre d'Exploration et de Recherche Médicale par Emission de Positons · FRCentre National de la Recherche Scientifique · FREvelina London Children's Healthcare · GBKing's College Hospital · GB

Funding

Medical Research Council MR/N013042/1
6 · The paper itself

Abstract

backgroundBrain [

resultsRegional SUVs showed similar patterns, but global values and resolutions were different as expected. Detection rates for the FCDs were 50% for comparison with the Marseille database and 53% for MRXFDG. Simply combining both databases worsened the detection rate to 41%. After harmonisation of spatial resolution, using a full factorial design matrix to accommodate global differences, and leaving out controls older than 60 years, we achieved detection rates of up to 71% for both databases combined. Detection rates were similar across the three scanner types used for patients, and high for patients whose MRI had been normal (n = 10/11).

conclusionsAs expected, global and regional data characteristics are database specific. However, our work shows the value of increasing database size and suggests ways in which database differences can be overcome. This may inform analysis via traditional statistics or machine learning, and clinical implementation.

Indexed as

Anomaly detectionHarmonisationInterscanner differencesSmoothnessStatistical parametric mapping (SPM)

Identifiers

PMID37964137
PMCPMC10645721
OpenAlexW4388703772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.