Evidence map›Paper›PMID 37963891›Full record

ArticleNature communications2023

Long-term cargo tracking reveals intricate trafficking through active cytoskeletal networks in the crowded cellular environment.

Jin-Sung Park, Il-Buem Lee, Hyeon-Min Moon, Seok-Cheol Hong, Minhaeng Cho

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Multifunctional biomolecular corona-inspired nanoremediation of antibiotic residues.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jin-Sung ParkCenter for Molecular Spectroscopy and Dynamics, Institute for Basic Science, Seoul, Korea.
Il-Buem LeeCenter for Molecular Spectroscopy and Dynamics, Institute for Basic Science, Seoul, Korea.
Hyeon-Min MoonCenter for Molecular Spectroscopy and Dynamics, Institute for Basic Science, Seoul, Korea.
Seok-Cheol HongCenter for Molecular Spectroscopy and Dynamics, Institute for Basic Science, Seoul, Korea. hongsc@korea.ac.kr.ORCID 0000-0001-5134-5912
Minhaeng ChoCenter for Molecular Spectroscopy and Dynamics, Institute for Basic Science, Seoul, Korea. mcho@korea.ac.kr.ORCID 0000-0003-1618-1056

Funding

Institute for Basic Science (IBS) IBS-R023-D1National Research Foundation of Korea (NRF) 2018K1A4A3A01064272National Research Foundation of Korea (NRF) NRF-2022R1A2B5B01002343
6 · The paper itself

Abstract

A eukaryotic cell is a microscopic world within which efficient material transport is essential. Yet, how a cell manages to deliver cellular cargos efficiently in a crowded environment remains poorly understood. Here, we used interferometric scattering microscopy to track unlabeled cargos in directional motion in a massively parallel fashion. Our label-free, cargo-tracing method revealed not only the dynamics of cargo transportation but also the fine architecture of the actively used cytoskeletal highways and the long-term evolution of the associated traffic at sub-diffraction resolution. Cargos frequently run into a blocked road or experience a traffic jam. Still, they have effective strategies to circumvent those problems: opting for an alternative mode of transport and moving together in tandem or migrating collectively. All taken together, a cell is an incredibly complex and busy space where the principle and practice of transportation intriguingly parallel those of our macroscopic world.

Indexed as

CytoskeletonMicroscopyBiological TransportMotion

Identifiers

PMID37963891
PMCPMC10645962

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.