ArticleeLife2023
Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
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Who cites it
36 citing papers in PubMed, 41 citations in OpenAlex.
- Rev-erb-α in Skeletal Muscle Adaptation: Integrating Circadian Control Mechanisms and Exercise Dynamic Responses.Journal of cellular physiology · 2026Review
- Self-organization of vascularized muscle from bovine embryonic stem cells.Nature communications · 2026Article
- Using human 3D organoid models to gain mechanistic insight in motor neuron diseases.Nature reviews. Neuroscience · 2026Review
- Systemic regeneration medicines for muscular dystrophy: progress and challenges in pro-regenerative drug development.Cell regeneration (London, England) · 2026Review
- iPSC-derived skeletal muscle spheroids for Duchenne Muscular Dystrophy modeling.Skeletal muscle · 2026Article
- Mechanobiological landscape of muscle stem cells.Skeletal muscle · 2026Review
- Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt-mTORC1 activation across multiple isogenic models.Experimental & molecular medicine · 2026Article
- Human neuromuscular organoids mimic cancer-induced muscle cachexia.Cell reports methods · 2026Article
- Unveiling FLNC variants: iPSC-derived myogenic cells as a model to study disease mechanisms.Skeletal muscle · 2026Article
- Skin Epidermal Progenitor Maintenance by the SRCAP-H2A.Z Axis Downstream to Extracellular Signal-Regulated Kinase and mTOR Signaling.The Journal of investigative dermatology · 2026Article
- Skeletal muscle reprogramming in peripheral nerve injury: mechanisms, therapeutic roles, and complication management.Experimental biology and medicine (Maywood, N.J.) · 2026Review
- TGFβ-Smad3 signaling restores cell-autonomous Srsf1-mediated splicing of fibronectin in aged skeletal muscle stem cells.Nature communications · 2025Article
- Delineating transcriptomic signatures of in vitro human skeletal muscle models in comparison to in vivo references.Stem cell reports · 2025Article
- Article
- RNA Delivery Using a Graphene Oxide-Polyethylenimine Hybrid Inhibiting Myotube Differentiation.ACS nanoscience Au · 2025Article
- Organoids for tissue repair and regeneration.Materials today. Bio · 2025Review
- Human Pluripotent Stem Cell-Derived Skeletal Muscle Organoid Model of Aging-Induced Sarcopenia.Journal of cachexia, sarcopenia and muscle · 2025Article
- Organoid-based tissue engineering for advanced tissue repair and reconstruction.Materials today. Bio · 2025Review
- Article
- Proteomic Profiling Towards a Better Understanding of Genetic Based Muscular Diseases: The Current Picture and a Look to the Future.Biomolecules · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 8 institutions in 4 countries.
Lampros MavrommatisRuhr University Bochum, Medical Faculty, Institute of Anatomy, Department of Anatomy and Molecular Embryology, Bochum, Germany.
Hyun-Woo JeongMax Planck Institute for Molecular Biomedicine, Sequencing Core Facility, Münster, Germany.ORCID 0000-0002-6976-6739
Urs KindlerRuhr University Bochum, Medical Faculty, Institute of Anatomy, Department of Anatomy and Molecular Embryology, Bochum, Germany.ORCID 0000-0001-9676-6323
Gemma Gomez-GiroLuxembourg Centre for Systems Biomedicine, LCSB, Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg.
Marie-Cecile KienitzRuhr University Bochum, Medical Faculty, Department of Cellular Physiology, Bochum, Germany.
Martin StehlingMax Planck Institute for Molecular Biomedicine, Flow Cytometry Unit, Münster, Germany.
Olympia E PsathakiMax Planck Institute for Molecular Biomedicine, Department of Cell and Developmental Biology, Münster, Germany.
Dagmar ZeuschnerMax Planck Institute for Molecular Biomedicine, Electron Microscopy Unit, Münster, Germany.ORCID 0000-0002-6712-0192
M Gabriele BixelMax Planck Institute for Molecular Biomedicine, Department of Tissue Morphogenesis, Münster, Germany.
Dong HanMax Planck Institute for Molecular Biomedicine, Department of Cell and Developmental Biology, Münster, Germany.
Gabriela Morosan-PuopoloRuhr University Bochum, Medical Faculty, Institute of Anatomy, Department of Anatomy and Molecular Embryology, Bochum, Germany.
Daniela GerovskaComputational Biology and Systems Biomedicine, Biodonostia Health Research Institute, San Sebastián, Spain.
Ji Hun YangSchool of Mechanical Engineering, Korea University, Seoul, Republic of Korea.
Jeong Beom KimSchool of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea.ORCID 0000-0001-6230-8826
Marcos J Arauzo-BravoComputational Biology and Systems Biomedicine, Biodonostia Health Research Institute, San Sebastián, Spain.ORCID 0000-0002-3264-464X
Jens C SchwambornLuxembourg Centre for Systems Biomedicine, LCSB, Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0003-4496-0559
Stephan A HahnRuhr University Bochum, Medical Faculty, Department of Molecular GI Oncology, Bochum, Germany.ORCID 0000-0003-0855-9741
Ralf H AdamsMax Planck Institute for Molecular Biomedicine, Department of Tissue Morphogenesis, Münster, Germany.ORCID 0000-0003-3031-7677
Hans R SchölerMax Planck Institute for Molecular Biomedicine, Department of Cell and Developmental Biology, Münster, Germany.
Matthias VorgerdDepartment of Neurology with Heimer Institute for Muscle Research, University Hospital Bergmannsheil, Bochum, Germany.
Beate Brand-SaberiRuhr University Bochum, Medical Faculty, Institute of Anatomy, Department of Anatomy and Molecular Embryology, Bochum, Germany.
Holm ZaehresRuhr University Bochum, Medical Faculty, Institute of Anatomy, Department of Anatomy and Molecular Embryology, Bochum, Germany.ORCID 0000-0001-8062-8428
Max Planck Institute for Molecular Biomedicine · DERuhr University Bochum · DEBiogipuzkoa Health Research Institute · ESUniversity of Luxembourg · LUKorea University · KROsnabrück University · DEUlsan National Institute of Science and Technology · KRUniversity of Münster · DE
Funding
Deutsche Duchenne Stiftung, Duchenne Deutschland e.V., DFP2018Deutsche Gesellschaft für Muskelkranke Za1/1
Abstract
In vitro culture systems that structurally model human myogenesis and promote PAX7
Indexed as
Muscle, SkeletalSatellite Cells, Skeletal MuscleCell DifferentiationFetusHumansMuscle DevelopmentPAX7 Transcription FactorPAX7 protein, humanPAX7 Transcription Factorhumanips cellsMyogenesisOrganoidsPax7regenerative medicinesatellite cellsskeletal musclestem cells
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.