Evidence map›Paper›PMID 37962696›Full record

ArticleInflammopharmacology2024

Anti-inflammatory potential of some eudesmanolide and guaianolide sesquiterpenes.

Shagufta Perveen, Azadeh Hamedi, Ardalan Pasdaran, Reza Heidari, Muhammad Shafiq Ul Azam, Sobia Tabassum, Rashad Mehmood, Jiangnan Peng

Abstract read
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In one paragraph

Article in Inflammopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Shagufta PerveenDepartment of Chemistry, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, MD, 21251, USA. shagufta792000@yahoo.com.
Azadeh HamediMedicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ardalan PasdaranMedicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. pasdaran@sums.ac.ir.ORCID http://orcid.org/0000-0001-6713-0756
Reza HeidariPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Muhammad Shafiq Ul AzamDepartment of Radiology, Yeovil district hospital Somerset foundation trust (NHS), BA21 4AT,, Yeovil, Somerset, UK.
Sobia TabassumInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University, Islamabad, Lahore Campus, Pakistan.
Rashad MehmoodDepartment of Chemistry, Division of Science and Technology, University of Education, Township, Lahore, Pakistan.
Jiangnan PengDepartment of Chemistry, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, MD, 21251, USA.
Shiraz University of Medical Sciences · IRMorgan State University · USCOMSATS University Islamabad · PKUniversity of Education · PKYeovil District Hospital NHS Foundation Trust · GB

Funding

Shiraz University of Medical Sciences 26099‎U.S. Food and Drug Administration ‎75F40119C10147‎
6 · The paper itself

Abstract

Ten sesquiterpene lactones isolated from Anvillea garcinii (Burm.f.) DC ethanolic extract were assessed for their anti-inflammatory potential by myeloperoxidase (MPO) activity assignment, and mice paw swelling model. 3α,4α-10β-trihydroxy-8α-acetyloxyguaian-12,6α-olide (1), epi-vulgarin (3), 9a-hydroxyparthenolide (4), garcinamine C (7), garcinamine D (8), garcinamine E (9), and 4, 9-dihydroxyguaian-10(14)-en-12-olide (10) showed explicit anti-inflammatory activity in rodent paw edema and MPO assignment. The findings of this study showed that the α-methylene γ-lactone moiety does not always guarantee an anti-inflammatory effect, but the presence of proline at the C

Indexed as

SesquiterpenesSesquiterpenes, GuaianeAnimalsAnti-Inflammatory AgentsLactonesMiceAnti-Inflammatory AgentseudesmanolideLactonesSesquiterpenesSesquiterpenes, GuaianeAnti-inflammatory potentialAnvillea garciniiSesquiterpene lactonesStructure–activity relationship

Identifiers

PMID37962696
OpenAlexW4388657020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.