Evidence map›Paper›PMID 37962610›Full record

ArticleAnalytical and bioanalytical chemistry2024

Study of Legionella pneumophila treatment with copper in drinking water by single cell-ICP-MS.

Lei Xu, Austin Sigler, Anna Chernatynskaya, Lindsey Rasmussen, Jingrang Lu, Endalkachew Sahle-Demessie, David Westenberg, Hu Yang, Honglan Shi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lei XuLinda and Bipin Doshi Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, MO, 65409, USA.
Austin SiglerDepartment of Chemistry and Center for Research in Energy and Environment, Missouri University of Science and Technology, Rolla, MO, 65409, USA.
Anna ChernatynskayaLinda and Bipin Doshi Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, MO, 65409, USA.
Lindsey RasmussenDepartment of Chemistry and Center for Research in Energy and Environment, Missouri University of Science and Technology, Rolla, MO, 65409, USA.
Jingrang LuOffice of Research and Development, US Environmental Protection Agency, Cincinnati, OH, USA.
Endalkachew Sahle-DemessieOffice of Research and Development, US Environmental Protection Agency, Cincinnati, OH, USA.
David WestenbergDepartment of Biological Sciences, Missouri University of Science and Technology, Rolla, MO, 65409, USA.
Hu YangLinda and Bipin Doshi Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, MO, 65409, USA. huyang@mst.edu.
Honglan ShiDepartment of Chemistry and Center for Research in Energy and Environment, Missouri University of Science and Technology, Rolla, MO, 65409, USA. honglan@mst.edu.ORCID http://orcid.org/0000-0002-0801-5683
Missouri University of Science and Technology · USEnvironmental Protection Agency · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Legionella pneumophila is a persistent opportunistic pathogen that poses a significant threat to domestic water systems. Previous studies suggest that copper (Cu) is an effective antimicrobial in water systems. A rapid and sensitive quantification method is desired to optimize the conditions of L. pneumophila treatment by Cu and to better understand the interaction mechanisms between Cu and cells. In this study, we developed a highly sensitive single cell (SC)-ICP-MS method to monitor L. pneumophila cell concentration and track their uptake of Cu. The SC-ICP-MS method showed excellent sensitivity (with a cell concentration detection limit of 1000 cells/mL), accuracy (good agreement with conventional hemocytometry method), and precision (relative standard deviation < 5%) in drinking water matrix. The cupric ions (Cu

Indexed as

Anti-Infective AgentsDrinking WaterLegionella pneumophilaCopperWater MicrobiologyWater SupplyAnti-Infective AgentsCopperDrinking WaterAntimicrobial resistanceCopper (Cu)Legionella pneumophilaSingle cell-ICP-MSViable but nonculturable cell (VBNC)Water treatment

Identifiers

PMID37962610
PMCPMC11077561
OpenAlexW4388670031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.