Evidence map›Paper›PMID 37962384›Full record

Trial reportSchizophrenia bulletin2024

Consent for Research Involving Spanish- and English-Speaking Latinx Adults With Schizophrenia.

Concepción Barrio, Dahlia Fuentes, Lize Tibiriçá, Mercedes Hernandez, Paula Helu-Brown, Shahrokh Golshan, Barton W Palmer

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Schizophrenia bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Concepción BarrioSuzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, CA, USA.
Dahlia FuentesSchool of Social Work, San Diego State University, San Diego, CA, USA.
Lize TibiriçáSam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, CA, USA.
Mercedes HernandezSteve Hicks School of Social Work, University of Texas, Austin, Austin, TX, USA.
Paula Helu-BrownDepartment of Psychology, Mount Saint Mary's University, Los Angeles, CA, USA.
Shahrokh GolshanDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Barton W PalmerDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-7618-3144
University of California San Diego · USMount St. Mary's University · USSan Diego State University · USThe University of Texas at Austin · USUniversity of Southern California · US

Funding

FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
Informed Consent for Latinos with SchizophreniaR01MH097274 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BARRIO, CONCEPCION, PALMER, BARTON W. · 2012 to 2014
$1.4M
NIH HHS R01 MH097274NIMH NIH HHS R01 MH097274NIMH NIH HHS T32 MH019934
6 · The paper itself

Abstract

backgroundLatinxs are vastly underrepresented in mental health research; one of many contributing factors may be complexities in the research consent process, including language preferences. We examined determinants of comprehension of research consent procedures and tested the effects of a preconsent research schema condition among 180 adults with schizophrenia (60 Latinx-English and 60 Latinx-Spanish preference, and 60 non-Latinx White). STUDY

designParticipants were randomly assigned (equal allocation) to an educational session regarding clinical research concepts and processes (schema condition) or to an attention control. Following a subsequent simulated consent procedure for a hypothetical drug trail, comprehension of consent disclosures was measured with 2 standard measures. STUDY

resultsOne-way ANOVAs showed significant medium effect size differences between ethnicity/language groups on both measures of comprehension (η2s = 0.066-0.070). The Latinx-Spanish group showed lower comprehension than non-Latinx White participants; differences between the 2 Latinx groups did not reach statistical significance. Group differences were not statistically significant after adjusting for differences in education, or on scores from structured measures of acculturation, health literacy, or research literacy. Two-way ANOVAs showed no significant main effects for consent procedure on either comprehension measure (Ps > .369; partial η2s < 0.006) and no significant group-by-consent interactions (Ps > .554; partial η2s < 0.008).

conclusionsAlthough the preconsent procedure was not effective, the results suggest health and research literacy may be targets for reducing disparities in consent comprehension. The onus is on researchers to improve communication of consent information as an important step to addressing health care disparities.

Indexed as

ComprehensionHispanic or LatinoInformed ConsentSchizophreniaAdultBiomedical ResearchFemaleHealth LiteracyHumansMaleMiddle AgedWhitedisparitiesethicsHispanicsinformed consentLatinosschizophrenia

Identifiers

PMID37962384
PMCPMC11059799
OpenAlexW4388653328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.