Evidence map›Paper›PMID 37962042›Full record

ReviewCurrent cancer drug targets2024

The Role of Vasodilator-stimulated Phosphoproteins in the Development of Malignant Tumors.

Jiandong Gui, Hangsheng Zhou, Hongyuan Wan, Dongjie Yang, Qing Liu, Lijie Zhu, Yuanyuan Mi

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current cancer drug targets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jiandong GuiWuxi School of Medicine, Jiangnan University, 1800 Lihudadao, Wuxi, 214122, Jiangsu Province, China.
Hangsheng ZhouWuxi School of Medicine, Jiangnan University, 1800 Lihudadao, Wuxi, 214122, Jiangsu Province, China.
Hongyuan WanWuxi School of Medicine, Jiangnan University, 1800 Lihudadao, Wuxi, 214122, Jiangsu Province, China.
Dongjie YangDepartment of Urology, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, Wuxi, 214122, Jiangsu Province, China.
Qing LiuDepartment of Urology, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, Wuxi, 214122, Jiangsu Province, China.
Lijie ZhuDepartment of Urology, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, Wuxi, 214122, Jiangsu Province, China.
Yuanyuan MiDepartment of Urology, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, Wuxi, 214122, Jiangsu Province, China.
Jiangnan University · CN

Funding

Clinical Trial of Affiliated Hospital of Jiangnan University LCYJ202227, LCYJ202323Double Hundred Medical Youth Professionals Program) from Health Committee of Wuxi BJ2020061Jiangnan University Wuxi School of Medicine 1286010242190070National Natural Science Foundation 81802576Research topic of Jiangsu Health Commission Z2022047Science and Technology Development Fund of Wuxi N20202021Wuxi Commission of Health and Family Planning T202102, J202012, Z202011
6 · The paper itself

Abstract

Vasodilator-stimulated phosphoprotein (VASP) is an actin-binding protein that includes three structural domains: Enabled/VASP homolog1 (EVH1), EVH2, and proline-rich (PRR). VASP plays an important role in various cellular behaviors related to cytoskeletal regulation. More importantly, VASP plays a key role in the progression of several malignant tumors and is associated with malignant cell proliferation, invasion, and metastasis. Here, we have summarized current studies on the impact of VASP on the development of several malignant tumors and their mechanisms. This study provides a new theoretical basis for clinical molecular diagnosis and molecular targeted therapy.

Indexed as

Cell Adhesion MoleculesMicrofilament ProteinsNeoplasmsPhosphoproteinsAnimalsCell ProliferationHumansVasodilator-Stimulated PhosphoproteinCell Adhesion MoleculesMicrofilament ProteinsPhosphoproteinsVasodilator-Stimulated Phosphoproteinbiomarkerfunction.invasionMalignant tumorsmetastasisvasodilator-stimulated phosphoprotein

Identifiers

PMID37962042
PMCPMC11092557
OpenAlexW4388657351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.