ArticleArthritis & rheumatology (Hoboken, N.J.)2024
Sustained Limb-Level Loading: A Ground Reaction Force Phenotype Common to Individuals at High Risk for and Those With Knee Osteoarthritis.
Article in Arthritis & rheumatology (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Are Altered Knee Joint Biomechanics Associated with Future Post-Traumatic Osteoarthritis Outcomes? A Systematic Review and Meta-Analysis of Longitudinal Studies.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Peak Vertical Ground Reaction Force Modifies Gait Biomechanics Bilaterally Following ACL Reconstruction: A Randomized Experiment.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Trial
- Increasing dynamic limb-level loading via real-time biofeedback decreases cumulative loading impulse during gait post-anterior cruciate ligament reconstruction.Clinical biomechanics (Bristol, Avon) · 2026Article
- Effects of Quadriceps Strength Recovery in the First Year After Anterior Cruciate Ligament Reconstruction on Gait Biomechanics.Sports health · 2026Article
- Step-by-step insight into gait analysis: A narrative review unlocking knee biomechanics.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Review
- Gait Biomechanical Profiles Following Anterior Cruciate Ligament Reconstruction in Sexually-Immature Pediatrics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Relation of vertical ground reaction forces while walking to contralateral structural worsening in adults with unilateral knee osteoarthritis: the Multicenter Osteoarthritis Study.Clinical biomechanics (Bristol, Avon) · 2026Article
- Design and Performance Study of a Gradient Honeycomb Vibration-Damping Structure for the Knee Joint.Biomimetics (Basel, Switzerland) · 2026Article
- Elastic Shape Analysis of Movement Data.Journal of the American Statistical Association · 2025Article
- Tibiofemoral Joint Contact Force Profiles of Pediatric Patients After Anterior Cruciate Ligament Reconstruction.The American journal of sports medicine · 2025Article
- Relationship Between Incidence of Knee Pain and Ground Reaction Force During Stepping Motion in Older Adults.Geriatrics (Basel, Switzerland) · 2025Article
- Bilateral waveform analysis of gait biomechanics presurgery to 12 months following ACL reconstruction compared to controls.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Exploring the Analgesic Effect of Acupuncture on Knee Osteoarthritis Based on MLT/cAMP/PKA/CREB Signaling Pathway.Journal of inflammation research · 2025Article
- Peak vertical ground reaction force used to identify sub-groups of individuals with differing biomechanical gait profiles post-anterior cruciate ligament reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
objectiveThe objective of this study was to compare the vertical (vGRF), anterior-posterior (apGRF), and medial-lateral (mlGRF) ground reaction force (GRF) profiles throughout the stance phase of gait (1) between individuals 6 to 12 months post-anterior cruciate ligament reconstruction (ACLR) and uninjured matched controls and (2) between ACLR and individuals with differing radiographic severities of knee osteoarthritis (KOA), defined as Kellgren and Lawrence (KL) grades KL2, KL3, and KL4.
methodsA total of 196 participants were included in this retrospective cross-sectional analysis. Gait biomechanics were collected from individuals 6 to 12 months post-ACLR (n = 36), uninjured controls matched to the ACLR group (n = 36), and individuals with KL2 (n = 31), KL3 (n = 67), and KL4 osteoarthritis (OA) (n = 26). Between-group differences in vGRF, apGRF, and mlGRF were assessed in reference to the ACLR group throughout each percentage of stance phase using a functional linear model.
resultsThe ACLR group demonstrated lower vGRF and apGRF in early and late stance compared to the uninjured controls, with large effects (Cohen's d range: 1.35-1.66). Conversely, the ACLR group exhibited greater vGRF (87%-90%; 4.88% body weight [BW]; d = 0.75) and apGRF (84%-94%; 2.41% BW; d = 0.79) than the KL2 group in a small portion of late stance. No differences in mlGRF profiles were observed between the ACLR and either the uninjured controls or the KL2 group. The magnitude of difference in GRF profiles between the ACLR and OA groups increased with OA disease severity.
conclusionIndividuals 6 to 12 months post-ACLR exhibit strikingly similar GRF profiles as individuals with KL2 KOA, suggesting both patient groups may benefit from targeted interventions to address aberrant GRF profiles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.