Evidence map›Paper›PMID 37961665›Full record

ArticlemedRxiv : the preprint server for health sciences2023

A Biallelic Variant of the RNA Exosome Gene

Milo B Fasken, Sara W Leung, Lauryn A Cureton, Maha Al-Awadi, Adila Al-Kindy, Sohail Khoshnevis, Homa Ghalei, Almundher Al-Maawali, Anita H Corbett

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Milo B FaskenDepartment of Biology, Emory College of Arts and Sciences, Atlanta, GA USA 30322.ORCID 0000-0003-4317-7909
Sara W LeungDepartment of Biology, Emory College of Arts and Sciences, Atlanta, GA USA 30322.
Lauryn A CuretonDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA USA 30322.ORCID 0000-0002-4098-1777
Maha Al-AwadiDepartment of Genetics, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Adila Al-KindySultan Qaboos University Hospital, Sultan Qaboos University, Muscat, Oman.
Sohail KhoshnevisDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA USA 30322.ORCID 0000-0001-7607-2041
Homa GhaleiDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA USA 30322.ORCID 0000-0003-0168-4654
Almundher Al-MaawaliDepartment of Genetics, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.ORCID 0000-0002-1404-8887
Anita H CorbettDepartment of Biology, Emory College of Arts and Sciences, Atlanta, GA USA 30322.ORCID 0000-0002-0461-6895
Emory and Henry College · USEmory University · USSultan Qaboos University Hospital · OMSultan Qaboos University · OM

Funding

Biogenesis of macromolecular machines for post-transcriptional regulation of translationR35GM138123 · NIGMS · EMORY UNIVERSITY · PI Homa Ghalei · 2020 to 2026
$3.0M
Genetics Predoctoral Training ProgramT32GM149422 · NIGMS · EMORY UNIVERSITY · PI TAMARA J. CASPARY · 2023 to 2026
$2.2M
Insight Into The RNA Processing And Decay Pathways Critical For Proper Neuronal Development And Function Through Focus On Mutations That Cause Pontocerebellar HypoplasiaR01GM130147 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CORBETT, ANITA H., VAN HOOF, AMBRO · 2018 to 2021
$1.4M
NIGMS NIH HHS R01 GM130147NIGMS NIH HHS R35 GM138123NIGMS NIH HHS T32 GM149422
6 · The paper itself

Abstract

The RNA exosome is an evolutionarily conserved complex required for both precise RNA processing and decay. Mutations in

Indexed as

EXOSC4neurodevelopmental disorderRNA ExosomeRNA processing/decaytranslation

Identifiers

PMID37961665
PMCPMC10635191
OpenAlexW4388011258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.