Evidence map›Paper›PMID 37961579›Full record

ArticlebioRxiv : the preprint server for biology2024

Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.

R J Mulligan, M M Magaj, L Digilio, S Redemann, C C Yap, B Winckler

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

R J MulliganDepartment of Cell Biology, University of Virginia, Charlottesville, VA.ORCID 0000-0001-8880-6938
M M MagajDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville VA.
L DigilioDepartment of Cell Biology, University of Virginia, Charlottesville, VA.
S RedemannDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville VA.
C C YapDepartment of Cell Biology, University of Virginia, Charlottesville, VA.
B WincklerDepartment of Cell Biology, University of Virginia, Charlottesville, VA.ORCID 0000-0002-7924-9313
University of Virginia · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007267 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GARCIA-BLANCO, MARIANO A. · 1985 to 2024
$13.4M
Organization and Function of Neuronal EndosomesR01NS083378 · NINDS · UNIVERSITY OF VIRGINIA · PI Bettina R Winckler · 2013 to 2026
$5.2M
Training in Cell and Molecular BiologyT32GM139787 · NIGMS · UNIVERSITY OF VIRGINIA · PI Bryce Paschal · 2021 to 2026
$2.5M
High-speed and high-resolution Zeiss880 multiphoton microscopy systemS10OD025156 · OD · UNIVERSITY OF VIRGINIA · PI PERIASAMY, AMMASI · 2019 to 2019
$600k
Mechanisms of Sensing and Responding to Lysosomal Stress in NeuronsR21NS128756 · NINDS · UNIVERSITY OF VIRGINIA · PI WINCKLER, BETTINA R · 2022 to 2022
$435k
Effects of Aging on Neuronal Lysosomal Damage Responses Driven by CMT2B-linked Rab7F30AG079497 · NIA · UNIVERSITY OF VIRGINIA · PI MULLIGAN, RYAN J · 2023 to 2025
$103k
NIA NIH HHS F30 AG079497NIGMS NIH HHS T32 GM007267NIGMS NIH HHS T32 GM139787NIH HHS S10 OD025156NINDS NIH HHS R01 NS083378NINDS NIH HHS R21 NS128756
6 · The paper itself

Abstract

Endosomal-lysosomal trafficking is accompanied by the acidification of endosomal compartments by the H

Indexed as

acidificationlate endosomelysosomal membrane permeabilizationmembrane traffickingRab7RILPV-ATPase

Identifiers

PMID37961579
PMCPMC10634777
OpenAlexW4388262376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.