Evidence map›Paper›PMID 37961493›Full record

ArticlebioRxiv : the preprint server for biology2023

Haematopoietic stem cell numbers are not solely determined by niche availability.

Shoichiro Takeishi, Tony Marchand, Wade R Koba, Daniel K Borger, Chunliang Xu, Chandan Guha, Aviv Bergman, Paul S Frenette, Kira Gritsman, Ulrich Steidl

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 4 countries.

Shoichiro Takeishi
Tony Marchand
Wade R Koba
Daniel K Borger
Chunliang Xu
Chandan Guha
Aviv Bergman
Paul S Frenette
Albert Einstein College of Medicine · USMontefiore Medical Center · US

Funding

Regulation and function of hematopoietic stem cell nichesR01DK056638 · NIDDK · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GRITSMAN, KIRA · 2000 to 2023
$8.7M
PI3 Kinase Inactivation in Myelodysplastic SyndromeR01DK130895 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI GRITSMAN, KIRA · 2022 to 2025
$2.2M
NIDDK NIH HHS R01 DK056638NIDDK NIH HHS R01 DK130895
6 · The paper itself

Abstract

Haematopoietic stem cells (HSCs) reside in specialized microenvironments, also referred to as niches, and it has been widely believed that HSC numbers are determined by the niche size alone

Identifiers

PMID37961493
PMCPMC10634881
OpenAlexW4388009793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.