Evidence map›Paper›PMID 37961483›Full record

ArticlebioRxiv : the preprint server for biology2024

Cortico-thalamic communication for action coordination in a skilled motor sequence.

Yi Li, Xu An, Patrick J Mulcahey, Yongjun Qian, X Hermione Xu, Shengli Zhao, Hemanth Mohan, Shreyas M Suryanarayana, Ludovica Bachschmid-Romano, Nicolas Brunel and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 3 countries.

Yi LiDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.ORCID 0000-0001-8025-1552
Xu AnDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.ORCID 0000-0003-3386-5521
Patrick J MulcaheyDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.
Yongjun QianDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.ORCID 0000-0002-2696-6730
X Hermione XuDepartment of Biomedical Engineering, Duke University, Durham, NC 27710, USA.ORCID 0000-0001-8682-2969
Shengli ZhaoDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.
Hemanth MohanDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.ORCID 0000-0002-1642-7581
Shreyas M SuryanarayanaDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.ORCID 0000-0001-9122-0399
Ludovica Bachschmid-RomanoDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.
Nicolas BrunelDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.
Ian Q WhishawDepartment of Neuroscience, Canadian Centre for Behavioural Research, University of Lethbridge, Lethbridge, AB, T1K 3M4, Canada.ORCID 0000-0001-5288-9882
Z Josh HuangDepartment of Neurobiology, Duke University, Durham, NC 27710, USA.ORCID 0000-0003-0592-028X
Duke University · USUniversity of Lethbridge · CA

Funding

Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
RNA-programmable cell-type targeting, editing, and therapyDP1MH129954 · NIMH · DUKE UNIVERSITY · PI HUANG, Z JOSH · 2021 to 2025
$5.6M
NIGMS NIH HHS T32 GM145449NIMH NIH HHS DP1 MH129954
6 · The paper itself

Abstract

The coordination of forelimb and orofacial movements to compose an ethological reach-to-consume behavior likely involves neural communication across brain regions. Leveraging wide-field imaging and photo-inhibition to survey across the cortex, we identified a cortical network and a high-order motor area (MOs-c), which coordinate action progression in a mouse reach-and-withdraw-to-drink (RWD) behavior. Electrophysiology and photo-inhibition across multiple projection neuron types within the MOs-c revealed differential contributions of pyramidal tract and corticothalamic (CT

Identifiers

PMID37961483
PMCPMC10634836
OpenAlexW4388191255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.