ArticlebioRxiv : the preprint server for biology2023
Altered PBP4 and GdpP functions synergistically mediate MRSA-like high-level, broad-spectrum β-lactam resistance in
Li-Yin Lai, Nidhi Satishkumar, Sasha Cardozo, Vijay Hemmadi, Leonor B Marques, Liusheng Huang, Sergio R Filipe, Mariana G Pinho, Henry F Chambers, Som S Chatterjee
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
10 authors at 4 institutions in 2 countries.
Li-Yin LaiDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland Baltimore, USA.
Nidhi SatishkumarDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland Baltimore, USA.
Sasha CardozoDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland Baltimore, USA.
Vijay HemmadiDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland Baltimore, USA.
Leonor B MarquesInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Liusheng HuangDrug Research Unit, Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2702-4486 Sergio R FilipeInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Mariana G PinhoInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.ORCID 0000-0002-7132-8842 Henry F ChambersDivision of Infectious Diseases, School of Medicine, University of California San Francisco, San Francisco, CA, USA.
Som S ChatterjeeDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland Baltimore, USA.ORCID 0000-0002-7138-4449 University of Maryland, Baltimore · USUniversidade Nova de Lisboa · PTUniversity of California, San Francisco · USRede de Química e Tecnologia · PT
Funding
Novel Mechanisms of Beta-lactam Resistance in Staph AureusR01AI100291 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI CHATTERJEE, SOM, HENRY CHAMBERS, HENRY F · 2013 to 2023
$5.1MSerine/threonine kinase signaling in beta-lactam resistance of Staphylococcus aureusR01AI165510 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Som Chatterjee · 2023 to 2026
$2.8MNIAID NIH HHS R01 AI100291NIAID NIH HHS R01 AI165510
6 · The paper itselfAbstract
Indexed as
gdpPMethicillin-Resistant Lacking mec (MRLM)pbp4β-lactam resistance
Identifiers
PMID37961375
PMCPMC10634853
OpenAlexW4387998595
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
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