Evidence map›Paper›PMID 37961358›Full record

ArticlebioRxiv : the preprint server for biology2024

Structural Requirements for Reverse Transcription by a Diversity-generating Retroelement.

Sumit Handa, Tapan Biswas, Jeet Chakraborty, Gourisankar Ghosh, Blair G Paul, Partho Ghosh

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sumit Handa
Tapan Biswas
Jeet Chakraborty
Gourisankar Ghosh
Blair G Paul
University of California San Diego · USMarine Biological Laboratory · US

Funding

MICROSCOPY &IMAGE ANALYSIS OF UNSTAINED MACROMOLECULESR01GM033050 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAKER, TIMOTHY S · 1985 to 2017
$4.3M
Suppressing Inflammation by Blocking IKK OligomerR01AI163327 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOURISANKAR GHOSH · 2022 to 2026
$2.6M
Selective infidelity in diversity-generating retroelementsR01GM132720 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PARTHO · 2020 to 2023
$1.3M
NIAID NIH HHS R01 AI163327NIGMS NIH HHS R01 GM033050NIGMS NIH HHS R01 GM132720
6 · The paper itself

Abstract

Diversity-generating retroelements (DGRs) create massive protein sequence variation in ecologically diverse microbes. Variation occurs during reverse transcription of a protein-encoding RNA template coupled to misincorporation at adenosines. In the prototypical

Identifiers

PMID37961358
PMCPMC10634737
OpenAlexW4387895668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.