Evidence map›Paper›PMID 37961356›Full record

ArticlebioRxiv : the preprint server for biology2023

Natural variation in oxytocin receptor signaling causes widespread changes in brain transcription: a link to the natural killer gene complex.

Arjen J Boender, Zachary V Johnson, George W Gruenhagen, Kengo Horie, Brianna E Hegarty, Jeffrey T Streelman, Hasse Walum, Larry J Young

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arjen J BoenderCenter for Translational Social Neuroscience, Silvio O. Conte Center for Oxytocin and Social Cognition, Emory National Primate Research Center, Emory University, Atlanta, GA, USA.ORCID 0000-0002-6018-3588
Zachary V JohnsonCenter for Translational Social Neuroscience, Silvio O. Conte Center for Oxytocin and Social Cognition, Emory National Primate Research Center, Emory University, Atlanta, GA, USA.ORCID 0000-0002-0101-6309
George W GruenhagenDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0001-6713-5370
Kengo HorieCenter for Translational Social Neuroscience, Silvio O. Conte Center for Oxytocin and Social Cognition, Emory National Primate Research Center, Emory University, Atlanta, GA, USA.ORCID 0000-0002-3709-9396
Brianna E HegartySchool of Biological Sciences, Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA.
Jeffrey T StreelmanSchool of Biological Sciences, Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA.
Hasse WalumMarcus Autism Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Larry J YoungCenter for Translational Social Neuroscience, Silvio O. Conte Center for Oxytocin and Social Cognition, Emory National Primate Research Center, Emory University, Atlanta, GA, USA.ORCID 0000-0003-2044-2239

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
The Impact of Oxytocin on the Neural Representation Social Stimuli P50MH100023 · NIMH · EMORY UNIVERSITY · PI YOUNG, LARRY J · 2013 to 2022
$21.8M
Genetic Regulation of Variability in Brain Oxytocin ReceptorsR01MH112788 · NIMH · EMORY UNIVERSITY · PI YOUNG, LARRY J · 2018 to 2022
$2.5M
Cellular basis of complex social behaviorR01GM144560 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI STREELMAN, JEFFERY TODD · 2022 to 2023
$723k
NIGMS NIH HHS R01 GM144560NIH HHS P51 OD011132NIMH NIH HHS P50 MH100023NIMH NIH HHS R01 MH112788
6 · The paper itself

Abstract

Oxytocin (OXT) is a highly conserved neuropeptide that modulates social cognition, and variation in its receptor gene (

Identifiers

PMID37961356
PMCPMC10634851

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.