Evidence map›Paper›PMID 37961343›Full record

ArticlebioRxiv : the preprint server for biology2023

Heterotypic responses against nsp12/nsp13 from prior SARS-CoV-2 infection associates with lower subsequent endemic coronavirus incidence.

David J Bean, Janet Monroe, Yan Mei Liang, Ella Borberg, Yasmeen Senussi, Zoe Swank, Sujata Chalise, David Walt, Janice Weinberg, Manish Sagar

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

David J BeanDepartment of Virology, Immunology and Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Janet MonroeDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Yan Mei LiangDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Ella BorbergDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Yasmeen SenussiDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Zoe SwankDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Sujata ChaliseDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
David WaltDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-5524-7348
Janice WeinbergDepartment of Biostatistics, Boston University School of Public Health, Boston, MA.
Manish SagarDepartment of Virology, Immunology and Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Boston University · USBrigham and Women's Hospital · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
HIV-1 mucosal transmission and persistenceK24AI145661 · NIAID · BOSTON MEDICAL CENTER · PI SAGAR, MANISH · 2019 to 2023
$908k
NIAID NIH HHS K24 AI145661NIAID NIH HHS P30 AI042853
6 · The paper itself

Abstract

Immune responses from prior SARS-CoV-2 infection and COVID-19 vaccination do not prevent re-infections and may not protect against future novel coronaviruses (CoVs). We examined the incidence of and immune differences against human endemic CoVs (eCoV) as a proxy for response against future emerging CoVs. Assessment was among those with known SARS-CoV-2 infection, COVID-19 vaccination but no documented SARS-CoV-2 infection, or neither exposure. Retrospective cohort analyses suggest that prior SARS-CoV-2 infection, but not COVID-19 vaccination alone, protects against subsequent symptomatic eCoV infection. CD8

Identifiers

PMID37961343
PMCPMC10634759
OpenAlexW4387903031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.