Evidence map›Paper›PMID 37961338›Full record

ArticlebioRxiv : the preprint server for biology2023

Rab27 in tick extracellular vesicle biogenesis and infection.

L Rainer Butler, Nisha Singh, Liron Marnin, Luisa M Valencia, Anya J O'Neal, Francy E Cabrera Paz, Dana K Shaw, Adela S Oliva Chavez, Joao H F Pedra

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

L Rainer ButlerThe University of Maryland Baltimore, Baltimore, Maryland, USA.
Nisha SinghThe University of Maryland Baltimore, Baltimore, Maryland, USA.
Liron MarninThe University of Maryland Baltimore, Baltimore, Maryland, USA.
Luisa M ValenciaThe University of Maryland Baltimore, Baltimore, Maryland, USA.
Anya J O'NealThe University of Maryland Baltimore, Baltimore, Maryland, USA.
Francy E Cabrera PazThe University of Maryland Baltimore, Baltimore, Maryland, USA.
Dana K ShawWashington State University, Pullman, Washington, USA.
Adela S Oliva ChavezTexas A&M University, College Station, Texas, USA.
Joao H F PedraThe University of Maryland Baltimore, Baltimore, Maryland, USA.ORCID 0000-0001-8740-2667
University of Maryland, Baltimore · USTexas A&M University · USWashington State University · US

Funding

Tick Resources CoreP01AI138949 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI Joao Pedra · 2018 to 2026
$13.5M
Ubiquitylation and Rickettsial Colonization of a Tick VectorR01AI116523 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PEDRA, JOAO · 2016 to 2025
$6.2M
Tick Saliva and Pathogen TransmissionR01AI134696 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Joao Pedra · 2018 to 2026
$5.1M
Tick-Pathogen Interactions: Exploring the Intersection between Stress Responses and ImmunityR01AI162819 · NIAID · WASHINGTON STATE UNIVERSITY · PI SHAW, DANA KATHLEEN · 2022 to 2025
$2.0M
Regulation of Skin Immunity by a Tick BiteR21AI165520 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PEDRA, JOAO · 2022 to 2023
$425k
Rab27 in tick extracellular vesicle biogenesisF31AI167471 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BUTLER, LILLIAN RAINER · 2022 to 2023
$77k
NIAID NIH HHS F31 AI167471NIAID NIH HHS P01 AI138949NIAID NIH HHS R01 AI116523NIAID NIH HHS R01 AI134696NIAID NIH HHS R01 AI162819NIAID NIH HHS R21 AI165520
6 · The paper itself

Abstract

Background: The blacklegged tick, Methods: Using BLAST, an Results: Our BLAST analysis identified several of the proteins involved in EV biogenesis in ticks, including Rab27. We show that silencing Conclusions: Rab27 is needed for successful tick feeding and may be important for acquiring

Indexed as

extracellular vesiclesRab27tick-borne diseasesTicks

Identifiers

PMID37961338
PMCPMC10635084
OpenAlexW4388298677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.