Evidence map›Paper›PMID 37961335›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Catherine Chanfreau-Coffinier, Kevin A Friede, Mary E Plomondon, Kyung Min Lee, Zhenyu Lu, Julie A Lynch, Scott L DuVall, Jason L Vassy, Stephen W Waldo, John H Cleator and 9 more

Registry-linked trialOpen access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06665919 (Randomized Controlled Trial for Evaluating CYP2C19 Allele Genotype-guided Clopidogrel Treatment Outcomes in Real-world Practice After the ePCI), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06665919 nacompletednot on this map

Randomized Controlled Trial for Evaluating CYP2C19 Allele Genotype-guided Clopidogrel Treatment Outcomes in Real-world Practice After the ePCI

TypeinterventionalSponsorVistamedi Ltd.Ran2023 to 2025Enrolled283ConditionsCoronary Artery Disease, Clopidogrel Resistance, Coronary Thrombosis, Adverse Cardiac EventsArmsCYP2C19 Genotype-Guided Clopidogrel Treatment, CYP2C19 Genotype Guided Antiplatelet Treatment Alternative to Clopidogrel, The Conventional Clopidogrel Treatment
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 11 institutions in 1 country.

Catherine Chanfreau-CoffinierVA Salt Lake City Heath Care System, Salt Lake City, UT.
Kevin A FriedeDivision of Cardiology, University of North Carolina School of Medicine, Chapel Hill, NC.
Mary E PlomondonCART Program, Office of Quality and Patient Safety, Veterans Health Administration, Washington, DC.ORCID 0000-0002-8616-4916
Kyung Min LeeVA Salt Lake City Heath Care System, Salt Lake City, UT.ORCID 0000-0001-8995-0448
Zhenyu LuVA Salt Lake City Heath Care System, Salt Lake City, UT.
Julie A LynchVA Salt Lake City Heath Care System, Salt Lake City, UT.ORCID 0000-0003-0108-2127
Scott L DuVallVA Salt Lake City Heath Care System, Salt Lake City, UT.
Jason L VassyVA Boston Healthcare System, Harvard Medical School, and Brigham and Women's Hospital, Boston, MA.
Stephen W WaldoCART Program, Office of Quality and Patient Safety, Veterans Health Administration, Washington, DC.ORCID 0000-0003-0678-4873
John H CleatorCentennial Heart at Skyline Medical Center, Nashville, TN.
Thomas M MaddoxWashington University School of Medicine in St. Louis, St. Louis, MO.ORCID 0000-0003-1426-9433
Daniel J RaderUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0002-9245-9876
Themistocles L AssimesVA Palo Alto Healthcare System and Stanford University, Palo Alto, CA.
Scott M DamrauerUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0001-8009-1632
Philip S TsaoVA Palo Alto Healthcare System and Stanford University, Palo Alto, CA.ORCID 0000-0001-7274-9318
Kyong-Mi ChangUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0001-6811-9364
Deepak VooraDurham VA Healthcare System and Duke University, Durham, NC.ORCID 0000-0003-0015-5179
Jay GiriUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0002-8076-0098
Sony TutejaUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0001-7007-3289
Philadelphia VA Medical Center · USVA Salt Lake City Healthcare System · USUniversity of Utah · USVA Palo Alto Health Care System · USVeterans Health Administration · USBrigham and Women's Hospital · USCentennial Medical Center · USDuke University · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · USWashington University in St. Louis · US

Funding

MULTIDISCIPLINARY HEART &VASCULAR DISEASEST32HL007101 · NHLBI · DUKE UNIVERSITY · PI FREEDMAN, NEIL J. · 1985 to 2020
$9.8M
Impact of the gut microbiome on response to lipid lowering therapyK23HL143161 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI TUTEJA, SONY · 2019 to 2022
$695k
BLRD VA I01 BX003362CSRD VA IK2 CX001780NHLBI NIH HHS K23 HL143161NHLBI NIH HHS T32 HL007101
6 · The paper itself

Abstract

Background: Objectives: Determine the association of Methods: Million Veterans Program (MVP) participants age <65 years with a PCI documented in the VA Clinical Assessment, Reporting and Tracking (CART) Program between 1/1/2009 to 9/30/2017, treated with clopidogrel were included. Time to MACE defined as the composite of all-cause death, stroke or myocardial infarction within 12 months following PCI. Results: Among 4,461 Veterans (mean age 59.1 ± 5.1 years, 18% Black); 44% had ACS, 56% had SIHD and 29% carried a Conclusions:

Indexed as

acute coronary syndromeclopidogrelCYP2C19 genotypepercutaneous coronary interventionstable ischemic heart disease

Identifiers

PMID37961335
PMCPMC10635203
OpenAlexW4388196457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.