Evidence map›Paper›PMID 37961325›Full record

ArticlebioRxiv : the preprint server for biology2024

Multilevel gene expression changes in lineages containing adaptive copy number variants.

Pieter Spealman, Carolina de Santana, Titir De, David Gresham

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Pieter SpealmanCenter for Genomics and Systems Biology, Department of Biology, New York University.ORCID 0000-0002-7105-284X
Carolina de SantanaLaboratório de Microbiologia Ambiental e Saúde Pública - Universidade Estadual de Feira de Santana (UEFS), Bahia.ORCID 0000-0002-9385-0199
Titir DeCenter for Genomics and Systems Biology, Department of Biology, New York University.ORCID 0000-0002-4006-4880
David GreshamCenter for Genomics and Systems Biology, Department of Biology, New York University.ORCID 0000-0002-4028-0364
New York University · USUniversidade Estadual de Feira de Santana · BR

Funding

Regulated and evolutionary responses to nutritional stressR35GM153419 · NIGMS · NEW YORK UNIVERSITY · PI David Gresham · 2024 to 2026
$1.8M
Constraints and Consequences of Copy Number VariationR01GM134066 · NIGMS · NEW YORK UNIVERSITY · PI GRESHAM, DAVID · 2020 to 2023
$1.2M
The adaptive potential of translational regulationF32GM131573 · NIGMS · NEW YORK UNIVERSITY · PI SPEALMAN, PIETER · 2019 to 2021
$144k
NIGMS NIH HHS F32 GM131573NIGMS NIH HHS R01 GM134066NIGMS NIH HHS R35 GM153419
6 · The paper itself

Abstract

Copy-number variants (CNVs) are an important class of recurrent variants that mediate adaptive evolution. While CNVs can increase the relative fitness of the organism, they can also incur a cost. We previously evolved populations of

Identifiers

PMID37961325
PMCPMC10634702
OpenAlexW4387866984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.