Evidence map›Paper›PMID 37961248›Full record

ArticlebioRxiv : the preprint server for biology2023

The shared genetic architecture and evolution of human language and musical rhythm.

Gökberk Alagöz, Else Eising, Yasmina Mekki, Giacomo Bignardi, Pierre Fontanillas, 23andMe Research Team, Michel G Nivard, Michelle Luciano, Nancy J Cox, Simon E Fisher and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Gökberk AlagözLanguage and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, The Netherlands.ORCID 0000-0003-0530-2780
Else EisingLanguage and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, The Netherlands.ORCID 0000-0001-9819-1260
Yasmina MekkiDepartment of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Giacomo BignardiLanguage and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, The Netherlands.ORCID 0000-0002-7439-0684
Pierre Fontanillas23andMe, Inc., Sunnyvale, CA, USA.
23andMe Research Team
Michel G NivardDepartment of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
Michelle LucianoDepartment of Psychology, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-7306-3008
Nancy J CoxVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Simon E FisherLanguage and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, The Netherlands.ORCID 0000-0002-3132-1996
Reyna L GordonDepartment of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-1643-6979

Funding

Neurobiological Markers of Rhythm: Risk and Resilience for Language AcquisitionR01DC016977 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GORDON, REYNA LEIGH · 2019 to 2023
$3.5M
Biomarkers of Rhythmic Communication: Integrating Foundational and Translational ApproachesDP2HD098859 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GORDON, REYNA LEIGH · 2018 to 2018
$2.4M
Mapping the Genetic and Neural Architecture of Human Rhythm and Communication TraitsK18DC017383 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GORDON, REYNA LEIGH · 2018 to 2019
$237k
NICHD NIH HHS DP2 HD098859NIDCD NIH HHS K18 DC017383NIDCD NIH HHS R01 DC016977
6 · The paper itself

Abstract

Rhythm and language-related traits are phenotypically correlated, but their genetic overlap is largely unknown. Here, we leveraged two large-scale genome-wide association studies performed to shed light on the shared genetics of rhythm (N=606,825) and dyslexia (N=1,138,870). Our results reveal an intricate shared genetic and neurobiological architecture, and lay groundwork for resolving longstanding debates about the potential co-evolution of human language and musical traits.

Identifiers

PMID37961248
PMCPMC10634981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.