Evidence map›Paper›PMID 37961227›Full record

ArticlebioRxiv : the preprint server for biology2025

Vectorized instructive signals in cortical dendrites during a brain-computer interface task.

Valerio Francioni, Vincent D Tang, Enrique H S Toloza, Norma J Brown, Mark T Harnett

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 21 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Valerio FrancioniMcGovern Institute for Brain Research, MIT, Cambridge, MA, USA.ORCID 0000-0002-2130-5204
Vincent D TangMcGovern Institute for Brain Research, MIT, Cambridge, MA, USA.
Enrique H S TolozaMcGovern Institute for Brain Research, MIT, Cambridge, MA, USA.
Norma J BrownMcGovern Institute for Brain Research, MIT, Cambridge, MA, USA.
Mark T HarnettMcGovern Institute for Brain Research, MIT, Cambridge, MA, USA.
McGovern Institute for Brain Research · USHarvard University · US

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Dendritic Computation and Representation of Head Direction in Retrosplenial CortexR01NS113079 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HARNETT, MARK THOMAS · 2019 to 2023
$2.2M
The role of top-down dendritic processing in credit assignment and cortical dynamicsR01MH135141 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Mark Thomas Harnett · 2024 to 2026
$2.1M
A dendritic mechanism for cholinergic neuromodulation of cortical functionR01NS106031 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HARNETT, MARK THOMAS · 2018 to 2022
$1.7M
NIGMS NIH HHS T32 GM007753NIMH NIH HHS R01 MH135141NINDS NIH HHS R01 NS106031NINDS NIH HHS R01 NS113079
6 · The paper itself

Abstract

Vectorization of teaching signals is a key element of virtually all modern machine learning algorithms, including backpropagation, target propagation and reinforcement learning. Vectorization allows a scalable and computationally efficient solution to the credit assignment problem by tailoring instructive signals to individual neurons. Recent theoretical models have suggested that neural circuits could implement single-phase vectorized learning at the cellular level by processing feedforward and feedback information streams in separate dendritic compartments

Identifiers

PMID37961227
PMCPMC10635122
OpenAlexW4388374118

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.