Evidence map›Paper›PMID 37961221›Full record

ArticlebioRxiv : the preprint server for biology2023

BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against

Miguel A B Mercado, Qiang Li, Charles M Quick, Yejin Kim, Rachel Palmer, Lu Huang, Lin-Xi Li

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Miguel A B MercadoDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205.
Qiang LiDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205.
Charles M QuickDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205.
Yejin KimDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205.
Rachel PalmerDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205.
Lu HuangDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205.ORCID 0000-0002-7820-2177
Lin-Xi LiDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205.ORCID 0000-0002-5526-8966
University of Arkansas for Medical Sciences · US

Funding

Study of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5M
Mechanisms of memory CD4 T cell-mediated immune protection against ChlamydiaR01AI139124 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI LI, LIN-XI · 2018 to 2022
$1.9M
Macrophage metabolism in diabetes and tuberculosis comorbidityR21AI175738 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI HUANG, LU · 2023 to 2024
$438k
NIAID NIH HHS R01 AI139124NIAID NIH HHS R21 AI175738NIGMS NIH HHS P20 GM103625
6 · The paper itself

Abstract

The protein basic helix-loop-helix family member e40 (BHLHE40) is a transcription factor recently emerged as a key regulator of host immunity to infections, autoimmune diseases and cancer. In this study, we investigated the role of

Indexed as

Bhlhe40Chlamydiafemale reproductive tractpolyfunctional CD4 T cells

Identifiers

PMID37961221
PMCPMC10635079
OpenAlexW4388373753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.