Evidence map›Paper›PMID 37961177›Full record

ArticlebioRxiv : the preprint server for biology2023

Neural and muscular contributions to the age-related loss in power of the knee extensors in men and women.

David J Wrucke, Andrew Kuplic, Mitchell Adam, Sandra K Hunter, Christopher W Sundberg

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David J WruckeExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.ORCID 0000-0003-4842-1405
Andrew KuplicExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.
Mitchell AdamExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.
Sandra K HunterExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.ORCID 0000-0001-8013-2051
Christopher W SundbergExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.ORCID 0000-0002-6709-4078
Marquette University · US

Funding

Fatigability of Limb Muscle in Older Adults: Protective Effects of ExerciseR01AG048262 · NIA · MARQUETTE UNIVERSITY · PI FITTS, ROBERT H, HUNTER, SANDRA K · 2015 to 2024
$6.1M
Motor Function in Older Adults: the Importance of Apolipoprotein-E ε4 InheritancR21AG045766 · NIA · MARQUETTE UNIVERSITY · PI HUNTER, SANDRA K · 2014 to 2015
$413k
Mechanisms of Neuromuscular Fatigue with AgingF31AG052313 · NIA · MARQUETTE UNIVERSITY · PI SUNDBERG, CHRISTOPHER · 2016 to 2017
$53k
NIA NIH HHS F31 AG052313NIA NIH HHS R01 AG048262NIA NIH HHS R21 AG045766
6 · The paper itself

Abstract

The mechanisms for the loss in limb muscle power in old (60-79 years) and very old (≥80 years) adults and whether the mechanisms differ between men and women are not well-understood. We compared maximal power of the knee extensor muscles between young, old, and very old men and women and identified the neural and muscular factors contributing to the age-related loss of power. 31 young (22.9±3.0 years, 15 women), 83 old (70.4±4.9 years, 39 women), and 16 very old adults (85.8±4.2 years, 9 women) performed maximal isokinetic contractions at 14 different velocities (30-450°/s) to identify peak power. Voluntary activation (VA) and contractile properties were assessed with transcranial magnetic stimulation to the motor cortex and electrical stimulation of the femoral nerve. The age-related loss in power was ~6.5 W·year

Indexed as

agingcontractile propertiespower-velocitysex differencesskeletal muscletorque-velocitytranscranial magnetic stimulationvoluntary activation

Identifiers

PMID37961177
PMCPMC10634815
OpenAlexW4388182122

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.