Evidence map›Paper›PMID 37961139›Full record

ArticlebioRxiv : the preprint server for biology2024

The Evolution of Heteroresistance via Small Colony Variants in

Teresa Gil-Gil, Brandon A Berryhill, Joshua A Manuel, Andrew P Smith, Ingrid C McCall, Fernando Baquero, Bruce R Levin

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Teresa Gil-GilDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0003-0136-3965
Brandon A BerryhillDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0003-3430-0901
Joshua A ManuelDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0001-6689-6549
Andrew P SmithDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0002-4848-3131
Ingrid C McCallDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.
Fernando BaqueroHospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, and Centro de Investigación Médica en Red, Epidemiología y Salud Pública (CIBERESP) Madrid, Spain.ORCID 0000-0002-7930-3033
Bruce R LevinDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0003-3600-2780
Emory University · USInstituto Ramón y Cajal de Investigación Sanitaria · ES

Funding

Single Cell Analysis Core (Core C)U19AI158080 · NIAID · EMORY UNIVERSITY · PI LEVIN, BRUCE RICHARD, WEISS, DAVID S · 2021 to 2025
$10.9M
Theoretical and Experimental Studies of the Population and Evolutionary Dynamics of Bacteria and Bacteriophage.R35GM136407 · NIGMS · EMORY UNIVERSITY · PI LEVIN, BRUCE RICHARD · 2020 to 2024
$2.0M
NIAID NIH HHS U19 AI158080NIGMS NIH HHS R35 GM136407
6 · The paper itself

Abstract

Traditionally, bacteriostatic antibiotics are agents able to arrest bacterial growth. Despite being traditionally viewed as unable to kill bacterial cells, when they are used clinically the outcome of these drugs is frequently as effective as when a bactericidal drug is used. We explore the dynamics of

Indexed as

antibiotic resistancebacteriostatic antibioticsEscherichia colievolutionHeteroresistancesmall colony variants

Identifiers

PMID37961139
PMCPMC10634941
OpenAlexW4388085648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.