Evidence map›Paper›PMID 37961114›Full record

ArticlebioRxiv : the preprint server for biology2023

Ciliary intrinsic mechanisms regulate dynamic ciliary extracellular vesicle release from sensory neurons.

Juan Wang, Josh Saul, Inna A Nikonorova, Carlos Nava Cruz, Kaiden M Power, Ken C Nguyen, David H Hall, Maureen M Barr

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Juan WangDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Josh SaulDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Inna A NikonorovaDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Carlos Nava CruzDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Kaiden M PowerDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Ken C NguyenCenter for C. elegans Anatomy, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
David H HallCenter for C. elegans Anatomy, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Maureen M BarrDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Rutgers, The State University of New Jersey · USAlbert Einstein College of Medicine · US

Funding

Polycystins, cilia, and extracellular vesicles in C. elegansR01DK059418 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI Maureen M Barr · 2001 to 2026
$9.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Nephronophthisis-related ciliopathies and ciliary specializationR01DK116606 · NIDDK · RUTGERS, THE STATE UNIV OF N.J. · PI Maureen M Barr · 2018 to 2026
$3.7M
Fundamental biology of neuronal extracellular vesicles - RenewalRF1NS120745 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI Maureen M Barr · 2021 to 2026
$3.0M
Fundamental Biology of Neuronal Extracellular VesiclesR01NS120745 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI BARR, MAUREEN M · 2024 to 2025
$785k
NIDDK NIH HHS R01 DK059418NIDDK NIH HHS R01 DK116606NIH HHS P40 OD010440NINDS NIH HHS R01 NS120745NINDS NIH HHS RF1 NS120745
6 · The paper itself

Abstract

Cilia-derived extracellular vesicles (EVs) contain signaling proteins and act in intercellular communication. Polycystin-2 (PKD-2), a transient receptor potential channel, is a conserved ciliary EVs cargo.

Indexed as

C. elegansceramideciliaDEGS1/2extracellular vesicleskinesin-3KLP-6NPHP-4PKD-2polycystin

Identifiers

PMID37961114
PMCPMC10635059
OpenAlexW4388344870

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.