Evidence map›Paper›PMID 37961113›Full record

ArticlebioRxiv : the preprint server for biology2023

Apobec-Mediated Retroviral Hypermutation

Hyewon Byun, Gurvani B Singh, Wendy Kaichun Xu, Poulami Das, Alejandro Reyes, Anna Battenhouse, Dennis C Wylie, Mary M Lozano, Jaquelin P Dudley

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hyewon Byun
Gurvani B Singh
Wendy Kaichun Xu
Poulami Das
Alejandro Reyes
Anna Battenhouse
Dennis C Wylie
Mary M Lozano
Jaquelin P DudleyORCID 0000-0002-1581-1098
The University of Texas at Austin · USTexas Center for Infectious Disease · US

Funding

Role of Apobecs in Retroviral ImmunityR01AI131660 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI DUDLEY, JAQUELIN PAGE · 2017 to 2021
$2.3M
NIAID NIH HHS R01 AI131660
6 · The paper itself

Abstract

Replication of the complex retrovirus mouse mammary tumor virus (MMTV) is antagonized by murine Apobec3 (mA3), a member of the Apobec family of cytidine deaminases. We have shown that MMTV-encoded Rem protein inhibits proviral mutagenesis by the Apobec enzyme, activation-induced cytidine deaminase (AID) during viral replication in BALB/c mice. To further study the role of Rem

Identifiers

PMID37961113
PMCPMC10635078
OpenAlexW4388300617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.