ArticlebioRxiv : the preprint server for biology2023
Molecular definition of distinct active zone protein machineries for Ca
Javier Emperador-Melero, Jonathan W Andersen, Sarah R Metzbower, Aaron D Levy, Poorna A Dharmasri, Giovanni de Nola, Thomas A Blanpied, Pascal S Kaeser
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 4 citations in OpenAlex.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
8 authors at 2 institutions in 1 country.
Javier Emperador-MeleroDepartment of Neurobiology, Harvard Medical School, Boston, USA.
Jonathan W AndersenDepartment of Neurobiology, Harvard Medical School, Boston, USA.
Sarah R MetzbowerDepartment of Physiology, University of Maryland School of Medicine, Baltimore, USA.
Aaron D LevyDepartment of Physiology, University of Maryland School of Medicine, Baltimore, USA.
Poorna A DharmasriDepartment of Physiology, University of Maryland School of Medicine, Baltimore, USA.
Giovanni de NolaDepartment of Neurobiology, Harvard Medical School, Boston, USA.
Thomas A BlanpiedDepartment of Physiology, University of Maryland School of Medicine, Baltimore, USA.
Harvard University · USUniversity of Maryland, Baltimore · US
Funding
VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI Irene M. Ghobrial · 1985 to 2026
$330.6MDissecting the assembly of vertebrate neurotransmitter release sites-Research Supplements to Promote Diversity in Health-Related ResearchR01MH113349 · NIMH · HARVARD MEDICAL SCHOOL · PI Pascal Simon Kaeser · 2017 to 2026
$6.1MMolecular Dissection of Active Zone Functions in Neurotransmitter ReleaseR01NS083898 · NINDS · HARVARD MEDICAL SCHOOL · PI Pascal Simon Kaeser · 2014 to 2026
$5.9MInternal Dynamics of the Postsynaptic DensityR37MH080046 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI Thomas A Blanpied · 2020 to 2026
$5.0MMolecular Mechanisms for Co‐Assembly of Endocytic and Exocytic Machineries at a SynapseK99NS129959 · NINDS · HARVARD MEDICAL SCHOOL · PI EMPERADOR MELERO, JAVIER · 2023 to 2024
$226kGlutamate receptor mediated organization of synaptic nanostructureF31MH117920 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI DHARMASRI, POORNA AKALANKA · 2018 to 2021
$112kNCI NIH HHS P30 CA006516NIMH NIH HHS F31 MH117920NIMH NIH HHS R01 MH113349NIMH NIH HHS R37 MH080046NINDS NIH HHS K99 NS129959NINDS NIH HHS R01 NS083898
6 · The paper itselfAbstract
Action potentials trigger neurotransmitter release with minimal delay. Active zones mediate this temporal precision by co-organizing primed vesicles with Ca
Identifiers
PMID37961089
PMCPMC10634917
OpenAlexW4388101358
What OpenQuestion holds
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