Rapid Colloidal Gold Immunoassay for Pharmacokinetic Evaluation of Vancomycin in the Cerebrospinal Fluid and Plasma of Beagle Dogs.

Yechang Guo, Shaofeng Wang, Peiyue Li, Pan Zhang, Wei Wang

Open access · goldAbstract read

In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 39% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yechang GuoSchool of Integrated Circuits, Peking University, Beijing 100871, China.ORCID 0000-0002-3862-6143

Shaofeng WangSchool of Engineering and Technology, China University of Geosciences (Beijing), Beijing 100083, China.

Peiyue LiSchool of Integrated Circuits, Peking University, Beijing 100871, China.ORCID 0000-0002-3370-2936

Pan ZhangSchool of Integrated Circuits, Peking University, Beijing 100871, China.

Wei WangSchool of Integrated Circuits, Peking University, Beijing 100871, China.

Peking University · CNChina University of Geosciences (Beijing) · CN

Funding

111 Project B18001The National Key Research and Development Program of China 2020YFC2005405

6 · The paper itself

Abstract

Vancomycin (VAN), a glycopeptide antibiotic, is the preferred therapeutic agent for treating Gram-positive bacteria. Rapid and precise quantification of VAN levels in cerebrospinal fluid (CSF) and plasma is crucial for optimized drug administration, particularly among elderly patients. Herein, we introduce a novel clinical test strip utilizing colloidal gold competitive immunoassay technology for the expedient detection of VAN. This test strip enables the detection of VAN concentrations in clinical samples such as plasma within 10 min and has a limit of detection of 10.3 ng/mL, with an inhibitory concentration 50% (IC

Indexed as

Gold ColloidVancomycinAgedAnimalsAnti-Bacterial AgentsChromatography, LiquidDogsHumansImmunoassayAnti-Bacterial AgentsGold ColloidVancomycincolloidal gold immunoassaypharmacokinetic studytest stripvancomycin

Identifiers

PMID37960677

DOI10.3390/s23218978

PMCPMC10649247

OpenAlexW4388380428

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.