Evidence map›Paper›PMID 37960532›Full record

ArticleSensors (Basel, Switzerland)2023

Graph Analysis of TMS-EEG Connectivity Reveals Hemispheric Differences following Occipital Stimulation.

Ilaria Siviero, Davide Bonfanti, Gloria Menegaz, Silvia Savazzi, Chiara Mazzi, Silvia Francesca Storti

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ilaria SivieroDepartment of Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.ORCID 0000-0003-2974-1569
Davide BonfantiPerception and Awareness (PandA) Lab., Department of Neuroscience, Biomedicine and Movement Science, University of Verona, Piazzale Ludovico Antonio Scuro 10, 37124 Verona, Italy.ORCID 0000-0001-7858-8244
Gloria MenegazDepartment of Engineering for Innovation Medicine, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.ORCID 0000-0002-6889-3461
Silvia SavazziPerception and Awareness (PandA) Lab., Department of Neuroscience, Biomedicine and Movement Science, University of Verona, Piazzale Ludovico Antonio Scuro 10, 37124 Verona, Italy.ORCID 0000-0002-5333-9046
Chiara MazziPerception and Awareness (PandA) Lab., Department of Neuroscience, Biomedicine and Movement Science, University of Verona, Piazzale Ludovico Antonio Scuro 10, 37124 Verona, Italy.ORCID 0000-0002-4966-9341
Silvia Francesca StortiDepartment of Engineering for Innovation Medicine, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.ORCID 0000-0002-8605-803X

Funding

Fondazione Cassa di Risparmio di Verona Vicenza Belluno e Ancona "Ricerca scientifica d'eccellenza 2018" 2018.0861MIUR D.M. 737/2021 AI4Health: empowering neurosciences with eXplainable AI methodsMIUR D.M. 737/2021 Neural correlates of perceptual awareness: from neural architecture to the preservation of conscious vision in brain tumor patientsMIUR PRIN 2017 2017TBA4KS_002NEXTGENERATIONEU (NGEU) and funded by the Ministry of University and Research (MUR), National Recovery and Resilience Plan (NRRP) A multiscale integrated approach to the study of the nervous system in health and disease (MNESYS) (DN. 1553 11.10.2022)REACT EU-PON Ricerca e Innovazione 2014-2020
6 · The paper itself

Abstract

(1) Background: Transcranial magnetic stimulation combined with electroencephalography (TMS-EEG) provides a unique opportunity to investigate brain connectivity. However, possible hemispheric asymmetries in signal propagation dynamics following occipital TMS have not been investigated. (2) Methods: Eighteen healthy participants underwent occipital single-pulse TMS at two different EEG sites, corresponding to early visual areas. We used a state-of-the-art Bayesian estimation approach to accurately estimate TMS-evoked potentials (TEPs) from EEG data, which has not been previously used in this context. To capture the rapid dynamics of information flow patterns, we implemented a self-tuning optimized Kalman (STOK) filter in conjunction with the information partial directed coherence (iPDC) measure, enabling us to derive time-varying connectivity matrices. Subsequently, graph analysis was conducted to assess key network properties, providing insight into the overall network organization of the brain network. (3) Results: Our findings revealed distinct lateralized effects on effective brain connectivity and graph networks after TMS stimulation, with left stimulation facilitating enhanced communication between contralateral frontal regions and right stimulation promoting increased intra-hemispheric ipsilateral connectivity, as evidenced by statistical test (

Indexed as

ElectroencephalographyEvoked PotentialsBayes TheoremBrainHumansTranscranial Magnetic Stimulationbrain functional connectivitygraph analysisoccipital stimulationTEPTMS–EEG

Identifiers

PMID37960532
PMCPMC10650175

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.