Evidence map›Paper›PMID 37960224›Full record

ArticleNutrients2023

Long-Term Prognosis in Relation to Vitamin D Status in Pediatric Solid Tumor Patients.

Nóra Kárász, Orsolya Juhász, Marcell Imrei, Miklós Garami

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nóra KárászFaculty of Medicine, Semmelweis University, 1085 Budapest, Hungary.ORCID 0009-0002-0007-7174
Orsolya JuhászPediatric Center, Semmelweis University, 1094 Budapest, Hungary.ORCID 0000-0001-9045-7888
Marcell ImreiCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0003-0175-7462
Miklós GaramiPediatric Center, Semmelweis University, 1094 Budapest, Hungary.ORCID 0000-0003-4298-2746
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypovitaminosis D is associated with oncogenesis, and the initial level of Vitamin D may play a role in determining long-term prognosis, relapse-free survival (RFS) and overall survival (OS). The purpose of our study was to follow up pediatric cancer patients for a long time in terms of their baseline Vitamin D level and disease outcomes.

methodsWe collected data on the initial 25(OH)D concentration in 117 children and examined their RFS and OS using Kaplan-Meier curves.

resultsThe initial 25(OH)D mean value in the relapsed group was 20.35 ng/mL (SE: 2.05) and in children without relapse it was 26.14 ng/mL (SE: 1.13). Both the relapse-free and overall Kaplan-Meier curves showed a tendency for children with lower serum Vitamin D concentrations to experience cancer recurrence or fatal outcomes sooner than patients with normal serum levels.

conclusionsOur results indicated a possible correlation between higher pretreatment serum Vitamin D concentrations and improved overall and relapse-free survival.

Indexed as

Vitamin DVitamin D DeficiencyChildHumansNeoplasm Recurrence, LocalPrognosisVitaminsVitamin DVitaminsfollow-upoverall survivalpediatric oncologyprognosisrelapse-free survivalVitamin D

Identifiers

PMID37960224
PMCPMC10650320
OpenAlexW4388190557

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.