Evidence map›Paper›PMID 37959893›Full record

ArticlePolymers2023

Three-Dimensional Printing of Graphene Oxide/Poly-L-Lactic Acid Scaffolds Using Fischer-Koch Modeling.

Thamires Santos da Silva, Bianca de Oliveira Horvath-Pereira, Leandro Norberto da Silva-Júnior, João Víctor Barbosa Tenório Fireman, Michel Mattar, Marcílio Félix, Rogerio Leone Buchaim, Ana Claudia Oliveira Carreira, Maria Angelica Miglino, Marcelo Melo Soares

Abstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thamires Santos da SilvaDepartament of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, SP, Brazil.ORCID 0000-0002-7848-8558
Bianca de Oliveira Horvath-PereiraDepartament of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, SP, Brazil.
Leandro Norberto da Silva-JúniorDepartament of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, SP, Brazil.ORCID 0000-0003-2628-8746
João Víctor Barbosa Tenório FiremanDepartament of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, SP, Brazil.ORCID 0000-0003-1329-6587
Michel MattarInstituto de Reabilitação Oro Facial Osteogenesis S/S LTDA, Vila Olimpia 04532-060, SP, Brazil.
Marcílio FélixDepartment of Animal Anatomy, University of Marilia, Mirante, Marília 17525-902, SP, Brazil.
Rogerio Leone BuchaimDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.ORCID 0000-0002-5881-2218
Ana Claudia Oliveira CarreiraDepartament of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, SP, Brazil.ORCID 0000-0002-9142-1155
Maria Angelica MiglinoDepartament of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, SP, Brazil.
Marcelo Melo SoaresInstituto de Reabilitação Oro Facial Osteogenesis S/S LTDA, Vila Olimpia 04532-060, SP, Brazil.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.488264/2020-00São Paulo Research Foundation 2021/05445-7
6 · The paper itself

Abstract

Accurately printing customizable scaffolds is a challenging task because of the complexity of bone tissue composition, organization, and mechanical behavior. Graphene oxide (GO) and poly-L-lactic acid (PLLA) have drawn attention in the field of bone regeneration. However, as far as we know, the Fischer-Koch model of the GO/PLLA association for three-dimensional (3D) printing was not previously reported. This study characterizes the properties of GO/PLLA-printed scaffolds in order to achieve reproducibility of the trabecula, from virtual planning to the printed piece, as well as its response to a cell viability assay. Fourier-transform infrared and Raman spectroscopy were performed to evaluate the physicochemical properties of the nanocomposites. Cellular adhesion, proliferation, and growth on the nanocomposites were evaluated using scanning electron microscopy. Cell viability tests revealed no significant differences among different trabeculae and cell types, indicating that these nanocomposites were not cytotoxic. The Fischer Koch modeling yielded satisfactory results and can thus be used in studies directed at diverse medical applications, including bone tissue engineering and implants.

Indexed as

biocompatibilitybone tissuespectroscopytrabecula

Identifiers

PMID37959893
PMCPMC10648465

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.