Evidence map›Paper›PMID 37959874›Full record

ArticleMolecules (Basel, Switzerland)2023

New Thiazolyl-Pyrazoline Derivatives as Potential Dual EGFR/HER2 Inhibitors: Design, Synthesis, Anticancer Activity Evaluation and In Silico Study.

Mariam M Fakhry, Amr A Mattar, Marwa Alsulaimany, Ebtesam M Al-Olayan, Sara T Al-Rashood, Hatem A Abdel-Aziz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

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  14. Design, Synthesis and Biological Assessment ofPharmaceuticals (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mariam M FakhryDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr 11829, Egypt.ORCID 0000-0002-1855-6918
Amr A MattarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr 11829, Egypt.ORCID 0000-0001-7004-8737
Marwa AlsulaimanyDepartment of Pharmacognosy & Pharmaceutical Chemistry, College of Pharmacy, Taibah University, Medina 42353, Saudi Arabia.ORCID 0009-0001-0208-2658
Ebtesam M Al-OlayanDepartment of Zoology, College of Science, King Saud University, Riyadh 11495, Saudi Arabia.ORCID 0000-0002-4041-9848
Sara T Al-RashoodDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Hatem A Abdel-AzizApplied Organic Chemistry Department, National Research Center, Cairo 12622, Egypt.ORCID 0000-0002-2606-2504
Egyptian Russian University · EGKing Saud University · SANational Water Research Center · EGTaibah University · SA

Funding

Researchers Supporting Project number (RSP-2023/103), King Saud University, Riyadh, Saudi Arabia. Project number (RSP-2023/103)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsProtein Kinase InhibitorsCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorErbB ReceptorsHumansLapatinibMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsEGFR protein, humanErbB ReceptorsLapatinibProtein Kinase Inhibitorsanti-cancerapoptosiscell cycleEGFRHER2thiazolyl-pyrazoline

Identifiers

PMID37959874
PMCPMC10647861
OpenAlexW4388408404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.