Evidence map›Paper›PMID 37959844›Full record

ArticleMolecules (Basel, Switzerland)2023

Therapeutic Study of Cinnamic Acid Derivative for Oxidative Stress Ablation: The Computational and Experimental Answers.

Oluwafemi Adeleke Ojo, Akingbolabo Daniel Ogunlakin, Rotdelmwa Filibis Maimako, Gideon Ampoma Gyebi, Christopher Busayo Olowosoke, Odunayo Anthonia Taiwo, Tobiloba Christiana Elebiyo, David Adeniyi, Bolaji David, Matthew Iyobhebhe and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Oluwafemi Adeleke OjoGood Health and Wellbeing Research Cluster, Bowen University, Iwo 232102, Nigeria.ORCID 0000-0001-9331-396X
Akingbolabo Daniel OgunlakinGood Health and Wellbeing Research Cluster, Bowen University, Iwo 232102, Nigeria.ORCID 0000-0002-1649-846X
Rotdelmwa Filibis MaimakoDepartment of Biochemistry, Landmark University, Omu-Aran 251101, Nigeria.
Gideon Ampoma GyebiNatural Products and Structural (Bio-Chem)-Informatics Research Laboratory (NpsBC-RI), Department of Biochemistry, Bingham University, Karu 961105, Nigeria.ORCID 0000-0002-1945-1739
Christopher Busayo OlowosokeDepartment of Biotechnology, Federal University of Technology, PMB 704 Futa Road, Akure 340252, Nigeria.ORCID 0000-0002-4315-3184
Odunayo Anthonia TaiwoDepartment of Biochemistry, Chrisland University, Abeokuta 110118, Nigeria.ORCID 0000-0001-8752-3290
Tobiloba Christiana ElebiyoDepartment of Biochemistry, Landmark University, Omu-Aran 251101, Nigeria.
David AdeniyiGood Health and Wellbeing Research Cluster, Bowen University, Iwo 232102, Nigeria.
Bolaji DavidGood Health and Wellbeing Research Cluster, Bowen University, Iwo 232102, Nigeria.
Matthew IyobhebheDepartment of Biochemistry, Landmark University, Omu-Aran 251101, Nigeria.ORCID 0000-0001-5198-1441
Juliana Bunmi AdetunjiDepartment of Biochemistry, Osun State University, Osogbo 232106, Nigeria.ORCID 0000-0002-3743-8773
Damilare IyinKristi AyokunleDepartment of Pure and Applied Biology, Bowen University, Iwo 232101, Nigeria.
Adebola Busola OjoDepartment of Biochemistry, Ekiti State University, Ado-Ekiti 362103, Nigeria.ORCID 0000-0003-1421-3819
Ramzi A MothanaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-4220-7854
Abdullah R AlanziDepartment of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.ORCID 0009-0000-2565-6573
Bowen University · NGLandmark University · NGKing Saud University · SABingham University · NGEkiti State University · NGFederal University of Technology · NGOsun State University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to examine the therapeutic activity of the cinnamic acid derivative KAD-7 (N'-(2,4-dichlorobenzylidene)-3-(4-methoxyphenyl) acrylohydrazide) on Fe

Indexed as

AntioxidantsOxidative StressAdenosine TriphosphatasesCinnamatesGlutathioneLiverAdenosine TriphosphatasesAntioxidantsCinnamatescinnamic acidGlutathioneADMET profilingcinnamic aciddensity functional theorylivermolecular docking simulationoxidative stresspurinergic function

Identifiers

PMID37959844
PMCPMC10648207
OpenAlexW4388333595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.