Evidence map›Paper›PMID 37959817›Full record

ArticleMolecules (Basel, Switzerland)2023

β-Cyclodextrin Nanophotosensitizers for Redox-Sensitive Delivery of Chlorin e6.

Jaewon Jo, Ji Yoon Kim, Je-Jung Yun, Young Ju Lee, Young-Il Jeong

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Jaewon JoGwangju Center, Korea Basic Science Institute, Gwangju 61186, Republic of Korea.
Ji Yoon KimGwangju Center, Korea Basic Science Institute, Gwangju 61186, Republic of Korea.
Je-Jung YunResearch Center for Environmentally Friendly Agricultural Life Sciences, Jeonnam Bioindustry Foundation, Jeonnam 58275, Republic of Korea.
Young Ju LeeGwangju Center, Korea Basic Science Institute, Gwangju 61186, Republic of Korea.
Young-Il JeongDepartment of Dental Materials, College of Dentistry, Chosun University, Gwangju 61452, Republic of Korea.ORCID 0000-0002-9832-4331
Korea Basic Science Institute · KRChonnam National University · KRChosun University · KRJeonnam Bioindustry Foundation · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to prepare redox-sensitive nanophotosensitizers for the targeted delivery of chlorin e6 (Ce6) against cervical cancer. For this purpose, Ce6 was conjugated with β-cyclodextrin (bCD) via a disulfide bond, creating nanophotosensitizers that were fabricated for the redox-sensitive delivery of Ce6 against cancer cells. bCD was treated with succinic anhydride to synthesize succinylated bCD (bCDsu). After that, cystamine was attached to the carboxylic end of bCDsu (bCDsu-ss), and the amine end group of bCDsu-ss was conjugated with Ce6 (bCDsu-ss-Ce6). The chemical composition of bCDsu-ss-Ce6 was confirmed with

Indexed as

beta-CyclodextrinsChlorophyllidesNanoparticlesPhotochemotherapyPorphyrinsUterine Cervical NeoplasmsAnimalsCell Line, TumorFemaleHeLa CellsHumansOxidation-ReductionPhotosensitizing AgentsReactive Oxygen Speciesbeta-CyclodextrinsChlorophyllidesPhotosensitizing AgentsphytochlorinPorphyrinsReactive Oxygen Speciescancer targetingchlorin e6photodynamic therapyredox-sensitiveβ-cyclodextrin

Identifiers

PMID37959817
PMCPMC10648776
OpenAlexW4388221709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.