Evidence map›Paper›PMID 37959774›Full record

ReviewMolecules (Basel, Switzerland)2023

The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review.

Zhiyi Xie, Ninghua Jiang, Minqiu Lin, Xinglishang He, Bo Li, Yingjie Dong, Suhong Chen, Guiyuan Lv

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  13. Frontiers in pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Zhiyi XieCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Ninghua JiangThe Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, China.
Minqiu LinCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Huzhou 313200, China.
Xinglishang HeCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Huzhou 313200, China.
Bo LiCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Huzhou 313200, China.
Yingjie DongCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Suhong ChenCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Guiyuan LvCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Zhejiang University of Technology · CNShanghai Innovative Research Center of Traditional Chinese Medicine · CNZhejiang Chinese Medical University · CNJiaxing University · CN

Funding

Jiaxing Science and Technology Plan Project 2022AY30025Jiaxing Science and Technology Plan Project SQGY202300066Key R&D Program of Zhejiang Province 2020C04020The National Natural Science Foundation of China 82274134
6 · The paper itself

Abstract

Tonic Chinese herbal medicine is a type of traditional Chinese medicine, and its primary function is to restore the body's lost nutrients, improve activity levels, increase disease resistance, and alleviate physical exhaustion. The body's immunity can be strengthened by its polysaccharide components, which also have a potent immune-system-protecting effect. Several studies have demonstrated that tonic Chinese herbal medicine polysaccharides can improve the body's immune response to tumor cells, viruses, bacteria, and other harmful substances. However, the regulatory mechanisms by which various polysaccharides used in tonic Chinese herbal medicine enhance immune function vary. This study examines the regulatory effects of different tonic Chinese herbal medicine polysaccharides on immune organs, immune cells, and immune-related cytokines. It explores the immune response mechanism to understand the similarities and differences in the effects of tonic Chinese herbal medicine polysaccharides on immune function and to lay the foundation for the future development of tonic Chinese herbal medicine polysaccharide products.

Indexed as

Drugs, Chinese HerbalCaffeineCytokinesImmunityMedicine, Chinese TraditionalPolysaccharidesCaffeineCytokinesDrugs, Chinese HerbalPolysaccharidesautoimmunitymechanisms of actionpolysaccharidestraditional Chinese medicine

Identifiers

PMID37959774
PMCPMC10648855
OpenAlexW4388076541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.